Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | TLR3 | O15455 | 1/20 | 0.39 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822007 | 0.78 | COXFA4 (0.52) | HSP90AA1COXFA4HIF1AMAPT | |
| SCHEMBL3455801 | 0.74 | HSP90AA1 (0.57) | HSP90AA1TLR3COXFA4HIF1AALDH1A1 | |
| SCHEMBL2353551 | 0.74 | TLR3 (0.41) | TLR3HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL2353554 | 0.74 | TLR3 (0.41) | TLR3HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3456261 | 0.72 | COXFA4 (0.61) | HSP90AA1TLR3COXFA4KMT2AALDH1A1 | |
| SCHEMBL7608955 | 0.67 | MAPT (0.46) | TLR3HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL13090968 | 0.67 | KMT2A (0.46) | TLR3MEN1KMT2AMAPT | |
| SCHEMBL9141913 | 0.66 | TLR3 (0.43) | TLR3MEN1KMT2AALDH1A1 | |
| SCHEMBL3319434 | 0.66 | KCNE1 (0.44) | TLR3MEN1KMT2A | |
| SCHEMBL3319440 | 0.66 | KCNE1 (0.44) | TLR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740225-A4 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL MYERS SQUIBB CO (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1740225-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105159-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-11-10 | — | — | WO | disclosed |