Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 15/20 | 0.42 |
| ▸ | MAOA | P21397 | 11/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3812737 | 0.95 | SIGMAR1 (0.43) | SIGMAR1MAOBMAOABCHEACHE | |
| SCHEMBL3811794 | 0.86 | SIGMAR1 (0.45) | SIGMAR1MAOBMAOASLC6A2SLC6A4 | |
| SCHEMBL3813063 | 0.85 | SIGMAR1 (0.47) | SIGMAR1BCHEACHESLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL3818244 | 0.85 | SIGMAR1 (0.44) | SIGMAR1MAOBMAOASLC6A2SLC6A4 | |
| Oxalic Acid SCHEMBL3816423 | 0.81 | SIGMAR1 (0.45) | SIGMAR1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3812998 | 0.81 | SIGMAR1 (0.47) | SIGMAR1MAOBMAOAACHECYP2A6 | |
| SCHEMBL3812050 | 0.81 | SIGMAR1 (0.47) | SIGMAR1ACHESLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3825610 | 0.80 | SIGMAR1 (0.46) | SIGMAR1MAOBMAOAACHECYP2A6 | |
| SCHEMBL3812405 | 0.78 | SIGMAR1 (0.50) | SIGMAR1CYP2A6 | |
| SCHEMBL3817651 | 0.77 | SIGMAR1 (0.51) | SIGMAR1SLC6A2SLC6A4SLC6A3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |