Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812313 | 0.85 | SIGMAR1 (0.54) | SIGMAR1SLC6A2SLC6A4SLC6A3GRIN2B | |
| SCHEMBL3812050 | 0.82 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL3810188 | 0.81 | SIGMAR1 (0.56) | SIGMAR1SLC6A2SLC6A4SLC6A3GRIN2B | |
| Hydrochloric Acid SCHEMBL3808199 | 0.80 | SIGMAR1 (0.55) | SIGMAR1SLC6A2SLC6A4SLC6A3GRIN2B | |
| SCHEMBL3813063 | 0.79 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A4SLC6A3CYP2A6 | |
| Oxalic Acid SCHEMBL3813466 | 0.77 | KDM4E (0.48) | SIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3815464 | 0.77 | SIGMAR1 (0.43) | SIGMAR1SLC6A2SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL10368304 | 0.76 | SIGMAR1 (0.51) | SIGMAR1SLC6A2SLC6A4SLC6A3CYP2A6 | |
| Oxalic Acid SCHEMBL3816423 | 0.76 | SIGMAR1 (0.45) | SIGMAR1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL3808291 | 0.75 | SIGMAR1 (0.53) | SIGMAR1SLC6A4SLC6A3CYP2A6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |