Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3812786 | 0.92 | CYP2A6 (0.41) | CYP2A6KCNH2BIRC5SIGMAR1SLC6A2 | |
| SCHEMBL3816407 | 0.87 | SIGMAR1 (0.53) | CYP2A6BIRC5SIGMAR1BCHE | |
| Hydrochloric Acid SCHEMBL3817320 | 0.86 | SIGMAR1 (0.52) | CYP2A6BIRC5SIGMAR1BCHE | |
| SCHEMBL3816113 | 0.84 | SIGMAR1 (0.55) | CYP2A6BIRC5SIGMAR1 | |
| SCHEMBL12269070 | 0.83 | CYP2A6 (0.54) | CYP2A6SIGMAR1CHRM2ADRA2ACHRM1 | |
| SCHEMBL8648137 | 0.83 | CYP2A6 (0.54) | CYP2A6SIGMAR1CHRM2ADRA2ACHRM1 | |
| SCHEMBL14402598 | 0.82 | CYP2A6 (0.56) | CYP2A6SIGMAR1CHRM2ADRA2ACHRM1 | |
| SCHEMBL3807907 | 0.81 | SIGMAR1 (0.51) | CYP2A6KCNH2BIRC5SIGMAR1HTR1A | |
| SCHEMBL3793629 | 0.80 | CYP2A6 (0.58) | CYP2A6SIGMAR1 | |
| SCHEMBL3822570 | 0.80 | SIGMAR1 (0.44) | CYP2A6SIGMAR1SLC6A4OPRM1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |