Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807325 | 0.90 | NPC1 (0.47) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2158675 | 0.87 | CRHBP (0.47) | CRHBPCRHR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL3809793 | 0.87 | NPC1 (0.41) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3809784 | 0.85 | MEN1 (0.44) | CRHBPCRHR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL3815496 | 0.83 | MEN1 (0.43) | CRHBPCRHR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3815444 | 0.83 | MEN1 (0.40) | CRHBPCRHR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3815779 | 0.82 | PTGES (0.41) | KMT2ACYP2C9NPC1RAB9A | |
| SCHEMBL3811495 | 0.82 | MAPT (0.38) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3809833 | 0.81 | PTGES (0.56) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2878959 | 0.81 | TSHR (0.40) | KMT2AMEN1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |