Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816635 | 0.80 | CA12 (0.41) | MEN1MAPTKMT2APOLBKDM4E | |
| SCHEMBL3936083 | 0.79 | LDHA (0.47) | MEN1MAPTKMT2APTPN2PTPRB | |
| SCHEMBL3808419 | 0.78 | TSHR (0.41) | MEN1MAPTKMT2APTPN2PTPRB | |
| SCHEMBL3811654 | 0.74 | KEAP1 (0.45) | MRGPRX4TDP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2083799 | 0.73 | NR4A1 (0.48) | MRGPRX4NR4A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20562338 | 0.72 | ESR1 (0.35) | MAPTESR2KDM4EALDH1A1GAA | |
| SCHEMBL30548341 | 0.72 | CYP1A2 (0.58) | MAPTESR2KDM4EASPHKDM8 | |
| SCHEMBL1713540 | 0.72 | CYP1A2 (0.58) | MAPTESR2KDM4EASPHKDM8 | |
| SCHEMBL9925245 | 0.71 | — | — | |
| SCHEMBL3815597 | 0.70 | CSNK2A1 (0.38) | MEN1MAPTKMT2APTPN2PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |