⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28049226 | 1.00 | ENPP2 (0.54) | — | |
| SCHEMBL29444147 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29779892 | 0.98 | ENPP2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL31187288 | 0.98 | ENPP2 (0.52) | — | |
| Formaldehyde SCHEMBL28227125 | 0.93 | ENPP2 (0.48) | — | |
| Boric Acid SCHEMBL29231593 | 0.91 | ENPP2 (0.62) | — | |
| SCHEMBL6776882 | 0.91 | ENPP2 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL3938787 | 0.89 | ENPP2 (0.46) | — | |
| SCHEMBL28444992 | 0.89 | GABRG2 (0.49) | — | |
| Bicarbonate SCHEMBL28730360 | 0.88 | ENPP2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2368 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2026-04-23 | — | — | US | claimed |
| EP-4467143-B1 | METHOD FOR PREPARING 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE | CELGENE CORP (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4430037-B1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORP (US) | 2025-10-29 | — | — | EP | claimed |
| CN-119866887-A | Rapid planting and propagation method by utilizing perennial leguminous forage vegetative propagules | 中国科学院植物研究所 | 2025-04-25 | — | — | CN | claimed |
| CN-119654316-A | Thioglutarimide isoindolinone skeleton-based compound and application thereof | 标新生物医药科技(上海)有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119451952-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2025-02-14 | — | — | CN | claimed |
| EP-3697410-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | TEIJIN PHARMA LTD (JP) | 2024-12-18 | — | — | EP | claimed |
| CN-118825397-A | Lithium ion battery electrolyte, preparation method thereof and lithium ion battery | 上海轩邑新能源发展有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118510775-A | Isoxazolidines as RIPK1 inhibitors and their use | 建新公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118398813-A | Positive electrode slurry, positive electrode sheet and secondary battery | 广东邦普循环科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| WO-2002072714-A1 | SOLUTIONS AND DISPERSIONS OF ORGANIC SEMICONDUCTORS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-09-19 | — | — | WO | claimed |
| EP-1175398-A1 | INDOLINE DERIVATIVES AS PROGESTERONE ANTAGONISTS | American Home Products Corporation (US) | 2002-01-30 | — | — | EP | claimed |
| WO-2000066556-A1 | INDOLINE DERIVATIVES AS PROGESTERONE ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| EP-0431373-B1 | Processes for producing 5-fluorbenzoic acids and their intermediates | ASAHI GLASS CO LTD (JP) | 1996-04-10 | — | — | EP | claimed |
| US-5332851-A | Trichloromethylating a fluorodihalobenzene, reaction with ammonia, hydrolysis of the nitrile | ASAHI GLASS COMPANY LTD. (JP) | 1994-07-26 | — | — | US | claimed |
| US-5241111-A | Trichloromethylating a fluorobenzene, reacting with aqueous ammonia, fluorinating, hydrolyzing | ASAHI GLASS COMPANY LTD. (JP) | 1993-08-31 | — | — | US | claimed |
| EP-0431373-A2 | Processes for producing 5-fluorbenzoic acids and their intermediates | ASAHI GLASS COMPANY LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4822903-A | Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-04-18 | — | — | US | claimed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | claimed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | claimed |