Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48794 | 0.81 | SIGMAR1 (0.53) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL48037 | 0.79 | SIGMAR1 (0.57) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL3817624 | 0.77 | SIGMAR1 (0.46) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL3809957 | 0.76 | SIGMAR1 (0.56) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| Hydrochloric Acid SCHEMBL3815309 | 0.75 | SIGMAR1 (0.55) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL3816500 | 0.74 | SIGMAR1 (0.56) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL4437379 | 0.74 | SIGMAR1 (0.53) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL3807967 | 0.73 | SIGMAR1 (0.45) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL6002906 | 0.73 | SIGMAR1 (0.54) | SIGMAR1CA2CA12CYP2A6PDE10A | |
| SCHEMBL13873189 | 0.73 | SIGMAR1 (0.57) | SIGMAR1CA2CA12CYP2A6PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |