SCHEMBL3816686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3818520	0.90	CYP3A4 (0.49)	CA2BTKADORA2AADORA1LMNA
	SCHEMBL14009836	0.88	HPGD (0.59)	HPGDALDH1A1CA2KDM4ELMNA
	SCHEMBL3815220	0.86	ROCK1 (0.52)	HPGDADORA2AADORA1ADORA3ADORA2B
	SCHEMBL3818878	0.86	SMN1; SMN2 (0.62)	HPGDADORA2AADORA1ADORA3ADORA2B
	SCHEMBL3818546	0.86	HTT (0.64)	HPGDALDH1A1ADORA2AADORA1ADORA3
	SCHEMBL3816956	0.83	MAPK1 (0.62)	HPGDCA2ADORA2AAURKAHSP90AA1
	SCHEMBL14009848	0.83	CYP3A4 (0.47)	HPGDALDH1A1CA2KDM4ELMNA
	SCHEMBL3819783	0.81	MMP13 (0.61)	CA2ADORA2ALMNAAURKAHSP90AA1
	SCHEMBL4923587	0.80	AKT3 (0.55)	HPGDALDH1A1BTKADORA2AADORA1
	SCHEMBL14021121	0.79	CAMK2D (0.55)	HPGDALDH1A1BTKSCN10ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.