SCHEMBL3816987

SCHEMBL3816987

CCO[Si](C)(CCCOCC1CO1)OCC.CO[Si](CCC1CCC2OC2C1)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9868126 1.00 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL7745321 0.94 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL6694355 0.94 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL14743070 0.93 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL18919601 0.92 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL8571810 0.91 TSHR (0.38) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL14875824 0.91 TSHR (0.38) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL2052975 0.91 TSHR (0.41) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL16666205 0.91 TSHR (0.41) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL26185870 0.90 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1631442-B1 LENS COATING CURING METHODS ESSILOR INT (FR) 2009-08-05 EP disclosed
EP-1631442-A1 LENS COATING CURING METHODS ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2006-03-08 EP disclosed
WO-2004101260-A1 LENS COATING CURING METHODS ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2004-11-25 WO disclosed
US-6051310-A Ophthalmic lens made of organic glass with a shockproof intermediate layer, and method for making same ESSILOR INTERNATIONAL-COMPAGNIE GENERALE D'OPTIQUE (FR) 2000-04-18 US disclosed
EP-0480426-B1 Polyarylene sulfide resin compositions MITSUBISHI RAYON CO (JP) 1998-01-28 EP disclosed