Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815310 | 0.91 | NPSR1 (0.62) | NPSR1KDM4ERXFP1FFAR4MEN1 | |
| SCHEMBL3815168 | 0.90 | NPSR1 (0.54) | NPSR1KDM4ERXFP1CYP2C9MCL1 | |
| SCHEMBL3809896 | 0.90 | ACLY (0.53) | NPSR1KDM4ERXFP1MAPTALDH1A1 | |
| SCHEMBL3811715 | 0.89 | NPSR1 (0.69) | NPSR1KDM4ERXFP1FFAR4MEN1 | |
| SCHEMBL3816532 | 0.88 | NPSR1 (0.69) | NPSR1KDM4ERXFP1MAPTHPGD | |
| SCHEMBL3812630 | 0.86 | ALDH1A1 (0.47) | NPSR1KDM4ERXFP1HPGDFFAR4 | |
| SCHEMBL3817013 | 0.85 | NPSR1 (0.53) | NPSR1KDM4ERXFP1MCL1 | |
| SCHEMBL2157818 | 0.84 | NPSR1 (0.73) | NPSR1KDM4ERXFP1MAPTHPGD | |
| SCHEMBL3811089 | 0.83 | NPSR1 (0.47) | NPSR1KDM4ERXFP1ALDH1A1MEN1 | |
| SCHEMBL3816575 | 0.81 | NPSR1 (0.67) | NPSR1KDM4ERXFP1MCL1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |