Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3813189 | 0.94 | SIGMAR1 (0.44) | SIGMAR1TSHRACHEBCHEKDM4E | |
| SCHEMBL3812050 | 0.88 | SIGMAR1 (0.47) | SIGMAR1TSHRCYP2A6ACHEKDM4E | |
| SCHEMBL3812877 | 0.87 | SIGMAR1 (0.46) | SIGMAR1TSHRCYP2A6PYCR1KDM4E | |
| SCHEMBL3817429 | 0.84 | SIGMAR1 (0.49) | SIGMAR1CYP2A6KCNH2PDE10ACA12 | |
| Oxalic Acid SCHEMBL3813466 | 0.84 | KDM4E (0.48) | SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL3812034 | 0.83 | SIGMAR1 (0.50) | SIGMAR1CYP2A6KCNH2PDE10ACA12 | |
| SCHEMBL3807994 | 0.83 | KCNH2 (0.47) | SIGMAR1CYP2A6PYCR1ACHEKCNH2 | |
| SCHEMBL3828050 | 0.82 | SIGMAR1 (0.49) | SIGMAR1CYP2A6KCNH2PDE10ACA12 | |
| SCHEMBL3810261 | 0.82 | SIGMAR1 (0.49) | SIGMAR1CYP2A6KCNH2PDE10ACA12 | |
| Oxalic Acid SCHEMBL3811672 | 0.82 | SIGMAR1 (0.45) | SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |