SCHEMBL3818112

SCHEMBL3818112

N#COC(=O)CCCC(=O)OC#N

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.32
DGKA P23743 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27853971 0.92 DGKA (0.38) TSHRDGKA
SCHEMBL11401849 0.92 DGKA (0.38) TSHRDGKA
SCHEMBL28619843 0.91 TSHR (0.52) TSHRSLC22A6CYP1A2
SCHEMBL8267112 0.89 ALDH1A1 (0.39) TSHR
SCHEMBL27788612 0.88 TSHR (0.38) TSHR
SCHEMBL10697867 0.87
SCHEMBL27853972 0.84 TSHR (0.52) TSHRSLC22A6CYP1A2
SCHEMBL27615017 0.84 TSHR (0.32) TSHRCYP1A2
SCHEMBL28555864 0.83 TSHR (0.32) TSHR
SCHEMBL11764440 0.82 DGKA (0.55) TSHRSLC22A6DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163590-A Soft and non-sticky high-color-fastness pigment printing adhesive and preparation method thereof 杭州传化精细化工有限公司 2022-03-11 CN claimed
US-6579469-B1 An adhesive composition that contains a preservative is particularly useful as a medical adhesive and can include alkyl cyanoacrylate monomers. The preservative is preferably soluble in the monomer. The composition may optionally be CLOSURE MEDICAL CORPORATION 2003-06-17 US claimed
US-6455064-B1 A KIT FOR DELIVERING A MEDICAMENT TO A PATIENT, COMPRISING A PACKAGE CONTAINING: A CONTAINER WITH DRUGS, CATALYSTS AND MONOMER CLOSURE MEDICAL CORPORATION 2002-09-24 US claimed
EP-1230313-A1 CYANOACRYLATE SOLUTIONS CONTAINING PRESERVATIVES Closure Medical Corporation (US) 2002-08-14 EP claimed
WO-2001032319-A9 ADHESIVE APPLICATOR CLOSURE MEDICAL CORP (US) 2002-08-08 WO claimed
WO-2001032795-A1 CYANOACRYLATE SOLUTIONS CONTAINING PRESERVATIVES CLOSURE MEDICAL CORPORATION (US) 2001-05-10 WO claimed
WO-2001032319-A2 ADHESIVE APPLICATOR CLOSURE MEDICAL CORPORATION (US) 2001-05-10 WO claimed
WO-2001030408-A2 ADHESIVE COMPOSITION OVER A BIOACTIVE POLYMERIZATION INITIATOR CLOSURE MEDICAL CORPORATION (US) 2001-05-03 WO claimed
CN-114163590-A Soft and non-sticky high-color-fastness pigment printing adhesive and preparation method thereof 杭州传化精细化工有限公司 2022-03-11 CN disclosed
US-10434211-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2019-10-08 US disclosed
US-10398802-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2019-09-03 US disclosed
US-10398800-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2019-09-03 US disclosed
US-20180243467-A1 ADHESIVE-CONTAINING WOUND CLOSURE DEVICE AND METHOD ETHICON, INC. 2018-08-30 US disclosed
US-20170216482-A1 Adhesive-Containing Wound Closure Device And Method ETHICON, INC. 2017-08-03 US disclosed
WO-2001032319-A2 ADHESIVE APPLICATOR CLOSURE MEDICAL CORPORATION (US) 2001-05-10 WO disclosed
WO-2001032795-A1 CYANOACRYLATE SOLUTIONS CONTAINING PRESERVATIVES CLOSURE MEDICAL CORPORATION (US) 2001-05-10 WO disclosed
WO-2001030408-A2 ADHESIVE COMPOSITION OVER A BIOACTIVE POLYMERIZATION INITIATOR CLOSURE MEDICAL CORPORATION (US) 2001-05-03 WO disclosed
WO-2000038777-A1 APPLICATOR FOR DISPENSABLE LIQUIDS CLOSURE MEDICAL CORPORATION (US) 2000-07-06 WO disclosed
US-4587059-A Process for production of 2-cyanoacrylates from 2,4-dicyanoglutarates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-05-06 US disclosed
US-4587059-A Process for production of 2-cyanoacrylates from 2,4-dicyanoglutarates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-05-06 US disclosed