SCHEMBL381885

SCHEMBL381885

NC(=O)c1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30092672 0.98
SCHEMBL7377426 0.98
Fumaric Acid SCHEMBL35210763 0.88 TSHR (0.33)
Trifluoroacetic Acid SCHEMBL28859339 0.87 HRH4 (0.39)
SCHEMBL30587567 0.85
SCHEMBL28947307 0.81 CCNC (0.30)
SCHEMBL9663668 0.80 P2RX7 (0.30)
SCHEMBL19281540 0.79 GDA (0.31)
SCHEMBL29486 0.78
Adenine SCHEMBL19057035 0.76 PI4KA (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731224-A1 DOSAGE REGIMENS FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES USING LY3871801 Eli Lilly and Company (US) 2026-04-29 EP claimed
EP-4055021-B1 HETEROCYCLIC RIP1 INHIBITORY COMPOUNDS RIGEL PHARMACEUTICALS INC (US) 2025-10-08 EP claimed
EP-4025568-B1 RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME RIGEL PHARMACEUTICALS INC (US) 2025-05-14 EP claimed
EP-4547335-A2 ANTI-SARS-COV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF Modex Therapeutics, Inc. (US) 2025-05-07 EP claimed
EP-4025574-B1 RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME RIGEL PHARMACEUTICALS INC (US) 2025-05-07 EP claimed
EP-4547711-A2 ANTI-SARS-COV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF Modex Therapeutics, Inc. (US) 2025-05-07 EP claimed
EP-3526209-B1 HETEROCYCLIC APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF RES TRIANGLE INST (US) 2025-04-16 EP claimed
CN-119836434-A Anti-SARS-CoV-2 antigen binding polypeptides, polypeptide complexes, and methods of use thereof 摩德斯医疗股份有限公司 2025-04-15 CN claimed
CN-119654311-A Carbobicyclic nucleosides for treatment of viral infections 香港中文大学 2025-03-18 CN claimed
CN-119528914-A Benzazepine ketone derivative and application thereof 杭州百诚医药科技股份有限公司 2025-02-28 CN claimed
EP-0220956-A2 Herbicidal 1,2,4-triazole-3-carboxamides KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-05-06 EP claimed
US-4614719-A REACTION OF 1,2,4-TRIAZOLE-CARBOXAMIDE AND RIBOSE DONOR IN PRESENCE OF BREVEBACTERIUM CATALYST YAMASA SHOYU KABUSHIKI KAISHA (JP) 1986-09-30 US claimed
US-4578479-A Process for preparing 1,2,4-triazole-3-carboxamides UBE INDUSTRIES, LTD. (JP) 1986-03-25 US claimed
US-4492597-A 1,5-Diphenyl derivative of 1,2,4-triazole-3-carboxamide and herbicide containing the same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-01-08 US claimed
EP-0070089-B1 1,2,4-TRIAZOLE DERIVATIVES HAVING HERBICIDAL ACTIVITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-12-05 EP claimed
EP-0126326-A1 Process for preparing 1,2,4-triazole-3-carboxamides UBE INDUSTRIES, LTD. (JP) 1984-11-28 EP claimed
EP-0027189-B1 2.5-DIKETOPIPERAZINE-DERIVATIVE, PROCESS FOR ITS PREPARATION AND ITS USE BAYER AG (DE) 1984-02-22 EP claimed
EP-0093401-A1 Process for producing ribavirin Yamasa Shoyu Kabushiki Kaisha (JP) 1983-11-09 EP claimed
EP-0070089-A1 1,2,4-Triazole derivatives having herbicidal activity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-01-19 EP claimed
US-3976545-A WITH NUCLEOSIDE PHOSPHORYLASE AND RIBOSE-1-PHOSPHATE TO FORM 1-B-D-RIBOFURANOSYL ICN PHARMACEUTICALS, INC. (US) 1976-08-24 US claimed