SCHEMBL29486

SCHEMBL29486

O=C(O)c1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28121890 0.98
SCHEMBL28124683 0.98
SCHEMBL253245 0.82 P2RX7 (0.30)
SCHEMBL9663668 0.82 P2RX7 (0.30)
SCHEMBL3212184 0.78
SCHEMBL1757260 0.78
SCHEMBL7377426 0.76
SCHEMBL4760562 0.75
SCHEMBL1608163 0.74 ALDH1A1 (0.48)
Fumaric Acid SCHEMBL35210763 0.73 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026103909-A1 MOF-BASED GLUCOSE DETECTION SYSTEM, SENSOR FOR DETECTING GLUCOSE CONCENTRATION IN SALIVA, AND NON-INVASIVE ORAL GLUCOSE METER 上海生物应用技术有限公司 2026-05-21 WO claimed
WO-2026105065-A1 METHODS AND SYSTEMS FOR METAL-ORGANIC FRAMEWORK SYNTHESIS, REPAIR, AND LIFETIME EXTENSION FOR SORPTIVE GAS SEPARATION APPLICATIONS SVANTE TECHNOLOGIES INC. (CA) 2026-05-21 WO claimed
US-12576387-B2 Porous metal-organic framework, method for producing the same, adsorbent, and method for separating carbon dioxide KABUSHIKI KAISHA TOSHIBA (JP) 2026-03-17 US claimed
EP-4695324-A1 BIO-ORTHOGONAL HYDROGELS FOR SUSTAINED RELEASE DRUG DELIVERY Ocular Therapeutix, Inc. (US) 2026-02-18 EP claimed
US-20260041785-A1 POLYGLYCEROL-CONJUGATED LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS COMPRISING THE SAME GENERATION BIO CO (US) 2026-02-12 US claimed
EP-4683964-A2 POLY(ETHYLENE GLYCOL) BASED DENDRIMER-LIKE HYPERBRANCHED MACROMOLECULES, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2026-01-28 EP claimed
EP-4665307-A1 BIODEGRADABLE MICROPARTICLES FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2025-12-24 EP claimed
WO-2025226726-A1 SURFACE-FUNCTIONALIZED MICROGELS AND USES THEREOF FOR T CELL EXPANSION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-10-30 WO claimed
US-20250326723-A1 Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly UNIV NORTHWESTERN (US) 2025-10-23 US claimed
EP-4626400-A1 NOVEL POLYGLYCEROL-CONJUGATED LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS COMPRISING THE SAME Generation Bio Co. (US) 2025-10-08 EP claimed
CN-1427722-A Method for treatment or prevention of flavivirus infections using nucleoside analogues SHIRE BIOCHEM INC (CA) 2003-07-02 CN claimed
US-20030078361-A1 Method of preparing aliphatic polyisocyanates with uretdione, isocyanurate and iminooxadiazindione structures BAYER AKTIENGESELLSCHAFT (DE) 2003-04-24 US claimed
WO-2003027275-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA ALCON, INC. (CH) 2003-04-03 WO claimed
US-20030013872-A1 Method of dimerizing isophorone diisocyanate BAYER AKTIENGESELLSCHAFT (DE) 2003-01-16 US claimed
EP-1186599-A1 NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES SHIONOGI & CO., LTD. (JP) 2002-03-13 EP claimed
US-6014998-A HAVING IMPROVED CURE RATE AND DYNAMIC MODULUS; MIXING ONE TRIAZOLE, SILICA AND COUPLING AGENT; TIRE RUBBER COMPONENTS PIRELLI PNEUMATICI S.P.A. (IT) 2000-01-18 US claimed
EP-0964028-A1 Silica reinforced tire compositions containing triazoles Pirelli Pneumatici S.p.A. (IT) 1999-12-15 EP claimed
EP-0027189-B1 2.5-DIKETOPIPERAZINE-DERIVATIVE, PROCESS FOR ITS PREPARATION AND ITS USE BAYER AG (DE) 1984-02-22 EP claimed
US-4312987-A Dimeric ketene of 1,2,4-triazole-3-carboxylic acid BAYER AKTIENGESELLSCHAFT (DE) 1982-01-26 US claimed
EP-0027189-A1 2.5-Diketopiperazine-derivative, process for its preparation and its use BAYER AG (DE) 1981-04-22 EP claimed