Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822986 | 0.86 | MAPK1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28485547 | 0.84 | ACE (0.56) | MAPK1PPARAPPARGACECTSS | |
| SCHEMBL28485548 | 0.84 | ACE (0.56) | MAPK1PPARAPPARGACECTSS | |
| SCHEMBL11598192 | 0.82 | REN (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL23040232 | 0.82 | PPARA (0.49) | PPARAPPARGACECTSSCTSL | |
| SCHEMBL26926036 | 0.82 | PPARA (0.49) | PPARAPPARGACECTSSCTSL | |
| SCHEMBL23040267 | 0.82 | PPARA (0.49) | PPARAPPARGACECTSSCTSL | |
| SCHEMBL3556150 | 0.80 | ACE (0.56) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3559433 | 0.80 | ACE (0.56) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29469354 | 0.78 | CTSS (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1625153-A1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099239-A1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |