Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177333 | 0.98 | CES2 (0.57) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL10885922 | 0.98 | CES2 (0.57) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11633109 | 0.98 | CES2 (0.57) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5177993 | 0.98 | CES2 (0.57) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11356070 | 0.98 | CES2 (0.57) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5176472 | 0.93 | CA2 (0.46) | CES2AKR1B1TSHRGPR84ALDH1A1 | |
| SCHEMBL2994868 | 0.88 | CES2 (0.61) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9246182 | 0.88 | CES2 (0.61) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3816304 | 0.84 | CES2 (0.52) | CES2AKR1B1PPARGPPARDPPARA | |
| SCHEMBL11094684 | 0.84 | CES2 (0.52) | CES2AKR1B1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361801-B1 | AUTOINDUCER COMPOUNDS AND THEIR USES | PATHWAY INTERMEDIATES LTD (GB) | 2007-06-06 | — | — | EP | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-1507010-B1 | Control of the gene expression in eukaryotic cells | CALGENE LLC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-7202085-B2 | Control of gene expression in eukaryotic cells | CALGENE LLC (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1190079-B1 | CONTROL OF GENE EXPRESSION IN EUKARYOTIC CELLS | CALGENE LLC (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20050227285-A1 | Control of gene expression in eukaryotic cells | MONSANTO COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-6943243-B2 | Control of gene expression in eukaryotic cells | CALGENE LLC (US) | 2005-09-13 | — | — | US | disclosed |
| EP-1507010-A2 | Control of the gene expression in eukaryotic cells | Calgene LLC (US) | 2005-02-16 | — | — | EP | disclosed |
| US-20030224483-A1 | Control of gene expression in eukaryotic cells | MONSANTO COMPANY | 2003-12-04 | — | — | US | disclosed |
| US-6518066-B1 | Control of gene expression in eukaryotic cells | CALGENE LLC | 2003-02-11 | — | — | US | disclosed |
| EP-1190079-A2 | CONTROL OF GENE EXPRESSION IN EUKARYOTIC CELLS | Calgene LLC (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001002593-A2 | CONTROL OF GENE EXPRESSION IN EUKARYOTIC CELLS | CALGENE LLC (US) | 2001-01-11 | — | — | WO | disclosed |
| US-4291036-A | Pyrido[1,2-A]pyrimidine derivatives and method of analgesic treatment | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-09-22 | — | — | US | disclosed |
| US-4219649-A | ANALGESICS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1980-08-26 | — | — | US | disclosed |