Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816257 | 1.00 | CAPN1 (0.33) | CAPN1CNR2CNR1BCHEGRIA2 | |
| SCHEMBL3816035 | 0.87 | ITGB3 (0.35) | — | |
| SCHEMBL3822022 | 0.83 | PTGDR2 (0.38) | CAPN1CNR2CNR1BCHE | |
| SCHEMBL3820116 | 0.83 | CAPN1 (0.34) | CAPN1BCHEGRIA2GRIN2AHCRTR1 | |
| SCHEMBL3816250 | 0.83 | CAPN1 (0.34) | CAPN1BCHEGRIA2GRIN2AHCRTR1 | |
| SCHEMBL3821711 | 0.81 | DPP4 (0.37) | BCHE | |
| SCHEMBL8187785 | 0.80 | GRM1 (0.33) | CAPN1BCHEGRIA2GRIN2AHCRTR1 | |
| SCHEMBL3822210 | 0.80 | GRIN2A (0.39) | GRIA2GRIN2AGRIN1 | |
| SCHEMBL3821866 | 0.80 | S1PR1 (0.38) | CNR2CNR1S1PR1 | |
| SCHEMBL3822208 | 0.79 | GRM1 (0.34) | GRIA2GRIN2AHCRTR1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091917-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008073934-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |