Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408462 | 1.00 | TSHR (0.57) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL1533154 | 1.00 | TSHR (0.57) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL16237875 | 0.98 | LMNA (0.55) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL2930714 | 0.90 | LMNA (0.50) | TSHRLMNANFKB1PMP22FFAR1 | |
| Hexane SCHEMBL2732468 | 0.90 | GPR84 (0.65) | TSHRFFAR1TDP1GPR84FFAR4 | |
| Water SCHEMBL6759104 | 0.88 | LMNA (0.48) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL14809347 | 0.87 | GPR84 (0.50) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL14359782 | 0.87 | GPR84 (0.50) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL14810362 | 0.87 | GPR84 (0.50) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL14360153 | 0.87 | GPR84 (0.50) | TSHRLMNANFKB1PMP22FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663319-B1 | METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL | UNIV CALIFORNIA (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-1663319-A4 | METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL | UNIV CALIFORNIA (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7357913-B2 | Methods for detecting, prognosing, or monitoring a disorder by comparing relative flux rates of two or more biological molecules in vivo | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-15 | — | — | US | disclosed |
| US-7262020-B2 | Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-28 | — | — | US | disclosed |
| US-20060204439-A1 | Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-09-14 | — | — | US | disclosed |
| EP-1663319-A2 | METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL | The Regents of the University of California (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005033652-A2 | METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-04-14 | — | — | WO | disclosed |
| WO-2005015155-A2 | METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005009597-A2 | METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20050019251-A1 | Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060204439-A1 | Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol | FABP1, SLC35B2, SLC10A1 | TSHR 443/4885LMNA 3952/4885NFKB1 1253/4885 |
| US-20050019251-A1 | Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol | FABP1, SLC35B2, SLC10A1 | TSHR 443/4885LMNA 3952/4885NFKB1 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.