Butyric Acid

Butyric Acid

SCHEMBL7907364

CCCC(=O)O.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
ALDH1A1 P00352 4/20 0.53
HPGD P15428 4/20 0.53
CYP1A2 P05177 4/20 0.53
HSD17B10 Q99714 3/20 0.53
KDM4E B2RXH2 3/20 0.53
CYP2D6 P10635 2/20 0.53
GLA P06280 1/20 0.53
POLB P06746 1/20 0.53
FFAR3 O14843 1/20 0.52
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
MEN1 O00255 4/20 0.49
TDP1 Q9NUW8 2/20 0.44
APEX1 P27695 1/20 0.42
THRB P10828 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL9435689 1.00 KMT2A (0.53) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Butyric Acid SCHEMBL10457170 0.94 KMT2A (0.51) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Butyric Acid SCHEMBL10457169 0.92 ALDH1A1 (0.54) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Pyrene SCHEMBL38210 0.90 HPGD (0.59) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Pyrene SCHEMBL9435802 0.90 HPGD (0.59) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Pyrene SCHEMBL30069714 0.90 HPGD (0.59) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Pyrene SCHEMBL9879158 0.88 HPGD (0.57) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Pyrene SCHEMBL28259646 0.88 HPGD (0.57) KMT2AALDH1A1HPGDCYP1A2HSD17B10
Octanoic Acid SCHEMBL3261656 0.88 GPR84 (0.57) KMT2AALDH1A1HSD17B10MEN1TDP1
Butyric Acid SCHEMBL27879291 0.87 KMT2A (0.43) KMT2AALDH1A1HPGDCYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102569657-A Preparation for photo-response Pyr-AZO non-covalent decorating carbon nano tube material UNIV TIANJIN 2012-07-11 CN disclosed
CN-100591265-C Skin-adhering sensor device PAUL HADVARY 2010-02-24 CN disclosed
CN-1976627-A Skin-adhering sensor device HADVARY PAUL (CH) 2007-06-06 CN disclosed
US-6210900-B1 Method of encoding a series of combinatorial libraries and developing structure activity relationships SMITHKLINE BEECHAM CORPORATION 2001-04-03 US disclosed
EP-0763202-A4 ENCODED COMBINATORIAL LIBRARIES SMITHKLINE BEECHAM CORP (US) 1998-12-09 EP disclosed
EP-0763202-A1 ENCODED COMBINATORIAL LIBRARIES SMITHKLINE BEECHAM CORPORATION (US) 1997-03-19 EP disclosed
WO-1995032425-A1 ENCODED COMBINATORIAL LIBRARIES SMITHKLINE BEECHAM CORPORATION (US) 1995-11-30 WO disclosed