Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3821146

C[Ge]1(C)C2=Cc3ccccc3C2[Zr+2]C2C1=Cc1ccccc12.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7783229 0.74 CYP11B1 (0.31) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL2450404 0.73 DRD2 (0.34) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL887737 0.73 DRD2 (0.34) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL5348306 0.70 DRD2 (0.33)
Hydrochloric Acid SCHEMBL547310 0.70 HTR2A (0.31)
Hydrochloric Acid SCHEMBL547374 0.70
Hydrochloric Acid SCHEMBL5348571 0.70
Hydrochloric Acid SCHEMBL3763829 0.70
Hydrochloric Acid SCHEMBL3645288 0.69 KDM1A (0.37) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL1277119 0.69 CYP19A1 (0.31) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2093268-B1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORP (JP) 2015-03-25 EP disclosed
EP-2123459-B1 Ink reservoir CANON KK (JP) 2012-06-06 EP disclosed
EP-2093268-A1 PRESSURE-SENSITIVE ADHESIVE SHEET Nitto Denko Corporation (JP) 2009-08-26 EP disclosed