Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746222 | 1.00 | ALOX5 (0.46) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL9745932 | 1.00 | ALOX5 (0.46) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL9745591 | 1.00 | ALOX5 (0.46) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL4539436 | 0.93 | HTT (0.43) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL7253715 | 0.86 | HPGD (0.39) | ALOX5CYP3A4MEN1TP53MAPT | |
| SCHEMBL222792 | 0.86 | TYR (0.55) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL38839 | 0.86 | TYR (0.55) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL29135897 | 0.86 | TYR (0.55) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL224251 | 0.86 | TYR (0.55) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL224790 | 0.86 | TYR (0.55) | ALOX5PTGS2TYRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406726-B1 | ORGANOALUMINIUM CATALYST, ITS PREPARATION AND ITS USE IN A PROCESS FOR THE POLYMERIZATION OF ALKYLENE OXIDES | UNION CARBIDE CHEM PLASTIC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7456127-B2 | Organoaluminum catalyst | UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION | 2008-11-25 | — | — | US | disclosed |
| US-20040142814-A1 | Organoaluminum catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC | 2004-07-22 | — | — | US | disclosed |
| EP-1406726-A2 | ORGANOALUMINIUM CATALYST, ITS PREPARATION AND ITS USE IN A PROCESS FOR THE POLYMERIZATION OF ALKYLENE OXIDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002098559-A2 | ORGANOALUMINUM CATALYST, ITS PREPARATION AND ITS USE IN A PROCESS FOR THE POLYMERIZATION OF ALKYLENE OXIDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY COR PORATION (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142814-A1 | Organoaluminum catalyst | AHR, LBR, NR1H3 | ALOX5 169/4885PTGS2 3250/4885TYR 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.