SCHEMBL4539436

SCHEMBL4539436

CCCCc1cc(C)cc(Sc2cc(C)cc(CCCC)c2O)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.43
HPGD P15428 2/20 0.43
NPC1 O15118 2/20 0.43
MAPK1 P28482 2/20 0.43
RAB9A P51151 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TYR P14679 3/20 0.41
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX5 P09917 5/20 0.39
PTGS2 P35354 3/20 0.38
TP53 P04637 3/20 0.37
MEN1 O00255 2/20 0.37
ALOX15 P16050 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
ALOX12 P18054 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745591 0.93 ALOX5 (0.46) HTTTYRMAPTALOX5PTGS2
SCHEMBL9745932 0.93 ALOX5 (0.46) HTTTYRMAPTALOX5PTGS2
SCHEMBL3821186 0.93 ALOX5 (0.46) HTTTYRMAPTALOX5PTGS2
SCHEMBL9746222 0.93 ALOX5 (0.46) HTTTYRMAPTALOX5PTGS2
SCHEMBL7253715 0.89 HPGD (0.39) HTTHPGDNPC1MAPK1RAB9A
SCHEMBL1755479 0.86 HTT (0.33) HTTHPGDNPC1MAPK1RAB9A
SCHEMBL21638088 0.85 HTT (0.38) HTTHPGDNPC1MAPK1RAB9A
SCHEMBL280118 0.85 TYR (0.48) HTTHPGDNPC1MAPK1RAB9A
SCHEMBL28665182 0.83 TYR (0.47) HTTHPGDNPC1MAPK1RAB9A
SCHEMBL29112780 0.83 TYR (0.47) HTTHPGDNPC1MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4353756-A1 ACRYLIC COPOLYMER, ACRYLIC-COPOLYMER-CONTAINING COMPOSITION, AND CROSSLINKED ACRYLIC COPOLYMER Osaka Soda Co., Ltd. (JP) 2024-04-17 EP disclosed
EP-3260500-B1 POLYAMIDE RESIN COMPOSITION, METHOD FOR PRODUCING POLYAMIDE RESIN COMPOSITION, AND MOLDED ARTICLE ASAHI CHEMICAL IND (JP) 2023-11-08 EP disclosed
WO-2023033043-A1 POLYAMIDE COMPOSITION 旭化成株式会社 2023-03-09 WO disclosed
US-11312832-B2 Thermoplastic resin composition for laser direct structuring process and article comprising the same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2022-04-26 US disclosed
US-11017918-B2 Semi-conductive composition for power cable DYM SOLUTION CO., LTD. (KR) 2021-05-25 US disclosed
US-10927232-B2 Polyamide resin composition, method for producing polyamide resin composition, and molded article ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-02-23 US disclosed
EP-3101054-B1 METHOD FOR GRANULATING POLYAMIDE OR POLYAMIDE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-04-22 EP disclosed
US-20190177499-A1 Thermoplastic Resin Composition for Laser Direct Structuring Process and Article Comprising the Same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2019-06-13 US disclosed
US-20190180889-A1 SEMI-CONDUCTIVE COMPOSITION FOR POWER CABLE DYM SOLUTION CO., LTD. (KR) 2019-06-13 US disclosed
EP-2724859-B1 MULTILAYER INJECTION-MOLDED BODY MITSUBISHI GAS CHEMICAL CO (JP) 2019-06-05 EP disclosed
US-20090226722-A1 CARBON BLACK UHIDA MASAFUMI 2009-09-10 US disclosed
US-20090214865-A1 CARBON BLACK KONICA MINOLTA BUSHINESS TECHNOLOGIES INC. (JP) 2009-08-27 US disclosed
US-20090085013-A1 Composition Containing Carbon Black, Composition for Coloring and Conductive Composition KONICA MINOLTA BUSINESS TECHNOLOGIES, INC., (JP) 2009-04-02 US disclosed
US-20090087766-A1 TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-02 US disclosed
US-20090035027-A1 DEVELOPING ROLLER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-02-05 US disclosed
US-20090011961-A1 Lubricant compositions stabilized with styrenated phenolic antioxidant CROMPTON HOLDING CORPORATION 2009-01-08 US disclosed
EP-1887049-A1 CARBON BLACK KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-02-13 EP disclosed
EP-1887050-A1 CARBON BLACK KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-02-13 EP disclosed
US-4125518-A 1-Oxa-4-azaspiro[4,5]decanes as light stabilizers for polymers AMERICAN CYANAMID COMPANY (US) 1978-11-14 US disclosed
US-4055540-A STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1977-10-25 US disclosed