⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20210832 | 0.84 | — | — | |
| SCHEMBL502089 | 0.81 | — | — | |
| SCHEMBL7627179 | 0.81 | — | — | |
| SCHEMBL20588662 | 0.81 | THRB (0.33) | — | |
| SCHEMBL13373282 | 0.67 | — | — | |
| SCHEMBL16235821 | 0.65 | — | — | |
| SCHEMBL29367874 | 0.56 | — | — | |
| SCHEMBL177556 | 0.55 | — | — | |
| SCHEMBL1378832 | 0.55 | — | — | |
| SCHEMBL127486 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203064-A | Novel benzamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INT | 2011-09-28 | — | — | CN | claimed |
| CN-101535304-A | Serine hydrolase inhibitors | ACTIVX BIOSCIENCES INC (US) | 2009-09-16 | — | — | CN | claimed |
| CN-101437811-A | Quinoline derivatives | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101437812-A | Quinoline derivatives for the treatment of cancer | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101432276-A | Quinoline derivatives | ASTRAZENECA AB (SE) | 2009-05-13 | — | — | CN | claimed |
| CN-100396668-C | Non-imidazole aryloxypiperidines | ORTHO MCNEIL PHARM INC (US) | 2008-06-25 | — | — | CN | claimed |
| CN-101137623-A | N-sulphonylpyrroles and their use as histone deacetylase inhibitors | NYCOMED GMBH (DE) | 2008-03-05 | — | — | CN | claimed |
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | claimed |
| CN-101119747-A | Tissue factor production inhibitor | SANKYO CO (JP) | 2008-02-06 | — | — | CN | claimed |
| CN-101094827-A | Benzene compound having two or more substituents | SANKYO CO (JP) | 2007-12-26 | — | — | CN | claimed |
| CN-1849121-A | Piperazine derivatives as bradyknin antagonist | AMGEN INC (US) | 2006-10-18 | — | — | CN | claimed |
| WO-2006044412-A1 | NOVEL B1 BRADYKININ RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | claimed |
| CN-1358194-A | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2002-07-10 | — | — | CN | claimed |
| CN-1290270-A | Streptogramin derivatives, preparation method and compositions containing them | AWENTIS PHARMACEUTICS S A (FR) | 2001-04-04 | — | — | CN | claimed |
| CN-1230187-A | Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors | GLAXO GROUP LTD (GB) | 1999-09-29 | — | — | CN | claimed |
| CN-1230185-A | Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors | GLAXO GROUP LTD (GB) | 1999-09-29 | — | — | CN | claimed |
| CN-1037574-C | Water soluble camptothecin analogs | SMITHKLINE BECKMAN CORP (US) | 1998-03-04 | — | — | CN | claimed |
| CN-1027265-C | Process for preparing water soluble camptothecin analogs | SMITHKLINE BECKMAN CORP (US) | 1995-01-04 | — | — | CN | claimed |
| CN-1083817-A | Water soluble camptothecin analogs | SMITHKLINE BECKMAN CORP (US) | 1994-03-16 | — | — | CN | claimed |
| CN-1034724-A | WATER SOLUBLE CAMPTOTHECIN ANALOGS | SMITHKLINE BECKMAN CORP (US) | 1989-08-16 | — | — | CN | claimed |