⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627179 | 1.00 | — | — | |
| SCHEMBL20588662 | 1.00 | THRB (0.33) | — | |
| SCHEMBL5326351 | 0.96 | — | — | |
| SCHEMBL20210832 | 0.89 | — | — | |
| SCHEMBL24733024 | 0.73 | GRIN1 (0.32) | — | |
| SCHEMBL2933795 | 0.73 | — | — | |
| SCHEMBL11888537 | 0.73 | — | — | |
| SCHEMBL22033682 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL22033837 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL10494046 | 0.69 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110835333-A | Benzimidazole substituted azole compound and application thereof | 中国药科大学 | 2020-02-25 | — | — | CN | claimed |
| CN-110835334-A | Indole-substituted azole compound and use thereof | 中国药科大学 | 2020-02-25 | — | — | CN | claimed |
| CN-110204741-A | A method of dispersion polysiloxanes Yu Shuizhong | 南京瑞思化学技术有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-101490063-B | Fluoroboron compound, aromatic ring aminomethylating agent comprising the same, and method for producing compound having aminomethyl aromatic ring using the aromatic ring aminomethylating agent | Sanitary Material R&D Management Co.,Ltd. (JP) | 2014-10-22 | — | — | CN | claimed |
| CN-103732210-A | Cosmetic compositions | WACKER CHEMIE AG | 2014-04-16 | — | — | CN | claimed |
| CN-101067023-B | Method for manufacturing organic silicon compound with carbamates | WAKE CHEMIE INC | 2010-11-03 | — | — | CN | claimed |
| CN-101490063-A | Fluoroboron compound, aromatic ring aminomethylating agent comprising the same, and method for producing compound having aminomethyl aromatic ring using the aromatic ring aminomethylating agent | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | claimed |
| CN-101067023-A | Method for manufacturing organic silicon compound with carbamates | WAKE CHEMIE INC (DE) | 2007-11-07 | — | — | CN | claimed |
| EP-1608652-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN MEDICINE | Vernalis (Cambridge) Limited (GB) | 2005-12-28 | — | — | EP | claimed |
| WO-2004087707-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN MEDICINE | VERNALIS (CAMBRIDGE) LIMITED (GB) | 2004-10-14 | — | — | WO | claimed |
| CN-1037574-C | Water soluble camptothecin analogs | SMITHKLINE BECKMAN CORP (US) | 1998-03-04 | — | — | CN | claimed |
| CN-1027265-C | Process for preparing water soluble camptothecin analogs | SMITHKLINE BECKMAN CORP (US) | 1995-01-04 | — | — | CN | claimed |
| CN-1083817-A | Water soluble camptothecin analogs | SMITHKLINE BECKMAN CORP (US) | 1994-03-16 | — | — | CN | claimed |
| EP-0206118-B1 | CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1992-07-22 | — | — | EP | claimed |
| CN-1034724-A | WATER SOLUBLE CAMPTOTHECIN ANALOGS | SMITHKLINE BECKMAN CORP (US) | 1989-08-16 | — | — | CN | claimed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | claimed |
| US-4703034-A | HYPOGLYCEMIC AGENT | MERCK & CO., INC. (US) | 1987-10-27 | — | — | US | claimed |
| EP-0206118-A2 | Cyclic hexapeptide somatostatin analogs, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-12-30 | — | — | EP | claimed |
| US-4612366-A | Cyclic hexapeptide somatostatin analogs | MERCK & CO., INC. (US) | 1986-09-16 | — | — | US | claimed |
| US-4611054-A | GLUCAGON, GROWTH HORMONE AND INSULIN RELEASE INHIBITORS | MERCK & CO., INC. (US) | 1986-09-09 | — | — | US | claimed |