SCHEMBL3821994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3828869	0.92	PTGIR (0.35)	EPHX1KMT2ACTSSCTSKALDH1A1
	SCHEMBL26999335	0.89	LMNA (0.39)	EPHX1CACNA1BMEN1MAPTKMT2A
	SCHEMBL20129230	0.85	LMNA (0.35)	EPHX1CACNA1BMEN1MAPTKMT2A
	SCHEMBL5092964	0.78	EPHX1 (0.42)	EPHX1CACNA1BMEN1MAPTKMT2A
	SCHEMBL17475891	0.78	LMNA (0.42)	EPHX1CACNA1BMEN1MAPTKMT2A
	SCHEMBL1142985	0.78	LMNA (0.38)	EPHX1MEN1MAPTKMT2AATM
	SCHEMBL6133282	0.77	LMNA (0.47)	EPHX1LMNANAAASPHK1SLC1A3
	SCHEMBL2375379	0.76	NR1H2 (0.43)	KMT2ACTSSCTSK
	SCHEMBL20335266	0.76	NR1H2 (0.43)	KMT2ACTSSCTSK
	SCHEMBL2375376	0.76	NR1H2 (0.43)	KMT2ACTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.