Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679687 | 0.83 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL205287 | 0.83 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL205286 | 0.83 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL10977192 | 0.83 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL467823 | 0.80 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL210386 | 0.80 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL467821 | 0.80 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL11206313 | 0.78 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3937605 | 0.75 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3937603 | 0.75 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391826-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES | Sanford Burnham Prebys Medical Discovery Institute | 2023-12-07 | — | — | US | claimed |
| WO-2022056473-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-03-17 | — | — | WO | claimed |
| US-20240219396-A1 | METHODS OF PREPARING SAMPLES FOR PROTEOMIC ANALYSIS | STRECK LLC | 2024-07-04 | — | — | US | disclosed |
| EP-4384619-A2 | RIBOSOMAL RNA (RRNA) VARIANTS POSSESSING ENHANCED PROTEIN PRODUCTION CAPABILITIES | The Broad Institute, Inc. (US) | 2024-06-19 | — | — | EP | disclosed |
| US-20240142444-A1 | DIAGNOSTIC METHOD FOR INFECTIOUS DISEASES | GEORGE MASON UNIVERSITY | 2024-05-02 | — | — | US | disclosed |
| WO-2024091897-A2 | DE NOVO DESIGNED MODULAR PEPTIDE BINDING PROTEINS BY SUPERHELICAL MATCHING | UNIVERSITY OF WASHINGTON (US) | 2024-05-02 | — | — | WO | disclosed |
| US-11965881-B2 | Nanosensors and methods for detection of biological markers | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2024-04-23 | — | — | US | disclosed |
| US-20240123059-A1 | Kaposi's Sarcoma Associated Herpesvirus Vaccine and Methods of Making and Using Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-04-18 | — | — | US | disclosed |
| US-20240125800-A1 | NANOSENSORS FOR RAPID IDENTIFICATION OF LUNG CONDITIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2024-04-18 | — | — | US | disclosed |
| EP-3494966-B1 | IMMUNE-MODIFYING PARTICLES FOR THE TREATMENT OF INFLAMMATION | ONCOUR PHARMA INC (US) | 2024-04-03 | — | — | EP | disclosed |
| EP-3042190-B1 | HIGH SENSITIVITY ELECTROSPRAY INTERFACE | UNIV NOTRE DAME DU LAC (US) | 2024-04-03 | — | — | EP | disclosed |
| EP-1317765-A2 | AUTOMATED IDENTIFICATION OF PEPTIDES | Oxford GlycoSciences (UK) Limited (GB) | 2003-06-11 | — | — | EP | disclosed |
| US-20020102610-A1 | Automated identification of peptides | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2002-08-01 | — | — | US | disclosed |
| WO-2002021139-A2 | AUTOMATED IDENTIFICATION OF PEPTIDES | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2002-03-14 | — | — | WO | disclosed |
| US-5905185-A | EXPERIMENTAL EVIDENCE INDICATES THAT PROTEIN C MAY BE CLINICALLY USEFUL IN THE TREATMENT OF THROMBOSIS. IN ADDITION, EXOGENOUS ACTIVATED PROTEIN C HAS BEEN SHOWN TO PREVENT THE COAGULOPATHIC AND LETHAL EFFECTS OF GRAM NEGATIVE SEPTICEMIA. | PPL THERAPEUTICS (GB) | 1999-05-18 | — | — | US | disclosed |
| EP-0874898-A1 | PROTEIN C PRODUCTION IN TRANSGENIC ANIMALS | ZymoGenetics, Inc. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997020043-A1 | PROTEIN C PRODUCTION IN TRANSGENIC ANIMALS | ZYMOGENETICS, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
| US-5079230-A | Reducing small-loop disulfide bonds and blocking the resulting sulfhydryl groups, storage stability | PITMAN-MOORE, INC. (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0433395-A1 | STABLE BIOACTIVE SOMATOTROPINS | MALLINCKRODT VETERINARY, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| WO-1990002758-A1 | STABLE BIOACTIVE SOMATOTROPINS | PITMAN-MOORE, INC. (US) | 1990-03-22 | — | — | WO | disclosed |