Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205287 | 1.00 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1679687 | 1.00 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL10977192 | 0.86 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL382217 | 0.83 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL210386 | 0.83 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL467821 | 0.83 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL467823 | 0.83 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL11206313 | 0.82 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL900182 | 0.77 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL900178 | 0.77 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200217854-A1 | MULTIPLEXED PROTEIN ASSAY FOR THE DETECTION OF MITOCHONDRIAL PROTEIN SIGNATURES | CEDARS-SINAI MEDICAL CENTER (US) | 2020-07-09 | — | — | US | disclosed |
| WO-2020113222-A1 | NEUROPROTECTIVE PDI MODULATING SMALL MOLECULES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2019060915-A2 | MULTIPLEXED PROTEIN ASSAY FOR THE DETECTION OF MITOCHONDRIAL PROTEIN SIGNATURES | CEDARS-SINAI MEDICAL CENTER (US) | 2019-03-28 | — | — | WO | disclosed |
| EP-2590675-B1 | RESPIRATORY SYNCYTIAL VIRUS ANTIGENIC COMPOSITIONS AND METHODS | ARTIFICIAL CELL TECH INC (US) | 2018-08-29 | — | — | EP | disclosed |
| US-20160046983-A1 | Method of Diagnosis of Infection by Mycobacteria and Reagents Therefor | TYRIAN DIAGNOSTICS LIMITED (AU) | 2016-02-18 | — | — | US | disclosed |
| EP-2436690-B1 | Reversibly photoswitchable polypeptides | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2015-12-23 | — | — | EP | disclosed |
| EP-1549750-B1 | MODULAR ANTIGEN TRANSPORTER MOLECULES (MAT MOLECULES) FOR MODULATING IMMUNE REACTIONS, ASSOCIATED CONSTRUCTS, METHODS AND USES THEREOF | BOEHRINGER INGELHEIM VETMED (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-20140322753-A1 | Polypeptides Having Endoglucanase Activity And Polynucleotides Encoding Same | NOVOZYMES AS (DK) | 2014-10-30 | — | — | US | disclosed |
| US-20140296481-A1 | Diagnosis and Monitoring of Renal Failure Using Peptide Biomarkers | PXBIOSCIENCES LLC (US) | 2014-10-02 | — | — | US | disclosed |
| US-8791328-B2 | Polypeptides having endoglucanase activity and polynucleotides encoding same | NOVOZYMES, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| EP-1272512-A2 | IMMUNOKINE COMPOSITION AND METHOD | PhyloMed Corporation (US) | 2003-01-08 | — | — | EP | disclosed |
| US-20020161325-A1 | Ultrasound catheter for improving blood flow to the heart | HANSMANN DOUGLAS R (US) | 2002-10-31 | — | — | US | disclosed |
| US-6312402-B1 | Ultrasound catheter for improving blood flow to the heart | EKOS CORPORATION | 2001-11-06 | — | — | US | disclosed |
| WO-2001070173-A2 | IMMUNOKINE COMPOSITION AND METHOD | PHYLOMED CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-2000016704-A1 | ULTRASOUND CATHETER FOR IMPROVING BLOOD FLOW TO THE HEART | EKOS CORPORATION (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-2000013025-A1 | STABLE ISOTOPE METABOLIC LABELING FOR ANALYSIS OF BIOPOLYMERS | UNIVERSITY OF WASHINGTON (US) | 2000-03-09 | — | — | WO | disclosed |
| US-5464774-A | DNA sequence | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1995-11-07 | — | — | US | disclosed |
| US-5155214-A | Basic fibroblast growth factor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-10-13 | — | — | US | disclosed |
| WO-1992015329-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1992-09-17 | — | — | WO | disclosed |
| US-4956455-A | POLYPEPTIDES CAPABLE OF STIMULATING GROWTH OF CELLS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1990-09-11 | — | — | US | disclosed |