Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.50 |
| ▸ | ME1 | P48163 | 1/20 | 0.50 |
| ▸ | ME3 | Q16798 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080907 | 0.92 | PTGS2 (0.72) | GSK3BPTGS2BACE1GSK3AME2 | |
| SCHEMBL12425030 | 0.86 | GSK3B (0.57) | GSK3BPTGS2BACE1GSK3ANR1H2 | |
| SCHEMBL4789169 | 0.84 | GSK3B (0.62) | GSK3BPTGS2GSK3A | |
| SCHEMBL18049442 | 0.84 | PTGS2 (0.62) | GSK3BPTGS2GSK3AME2ME1 | |
| SCHEMBL4684025 | 0.82 | GSK3B (0.89) | GSK3BGSK3ANR1H2NR1H3 | |
| SCHEMBL7781089 | 0.82 | GSK3B (1.00) | GSK3BGSK3ANR1H2NR1H3MAPT | |
| SCHEMBL114611 | 0.82 | PTGS2 (0.67) | GSK3BPTGS2PDE4B | |
| SCHEMBL3677953 | 0.81 | GSK3B (0.60) | GSK3BPTGS2BACE1GSK3AME2 | |
| SCHEMBL13141855 | 0.81 | BACE1 (0.62) | GSK3BBACE1NR1H2NR1H3PDE4B | |
| SCHEMBL9723700 | 0.81 | BACE1 (0.62) | GSK3BBACE1NR1H2NR1H3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-2091531-A2 | PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT | Congenia S.r.l. (IT) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008067863-A2 | PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT | CONGENIA S.R.L. (IT) | 2008-06-12 | — | — | WO | disclosed |