Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.62 |
| ▸ | PRKCA | P17252 | 4/20 | 0.62 |
| ▸ | STK10 | O94804 | 4/20 | 0.58 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | NEK2 | P51955 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669622 | 0.85 | GSK3B (0.60) | GSK3BPRKCASTK10SLKCHEK1 | |
| SCHEMBL3822337 | 0.84 | GSK3B (0.69) | GSK3BGSK3APTGS2 | |
| SCHEMBL5892139 | 0.81 | GAA (0.53) | GSK3BPRKCASTK10SLKCHEK1 | |
| SCHEMBL114611 | 0.78 | PTGS2 (0.67) | GSK3BPTGS2 | |
| SCHEMBL18049424 | 0.77 | PTGS2 (0.57) | GSK3BPTGS2 | |
| SCHEMBL211025 | 0.77 | PDE4B (0.59) | GSK3BSTK10SLKPTGS2 | |
| SCHEMBL28527835 | 0.76 | MAOA (0.50) | GSK3BPRKCASTK10SLKGSK3A | |
| SCHEMBL28080907 | 0.76 | PTGS2 (0.72) | GSK3BGSK3APTGS2 | |
| SCHEMBL29740761 | 0.76 | CYP1A1 (0.64) | — | |
| SCHEMBL458391 | 0.76 | CYP1A1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |