Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572448 | 0.91 | FDPS (0.47) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL14859749 | 0.85 | FDPS (0.54) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL15229941 | 0.84 | FDPS (0.44) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL16389746 | 0.84 | FDPS (0.51) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL2231149 | 0.84 | FDPS (0.51) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| Phosphoric Acid SCHEMBL2030112 | 0.84 | FDPS (0.54) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| Methyl Phosphonate SCHEMBL14738665 | 0.82 | FDPS (0.53) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL1289989 | 0.80 | FDPS (0.54) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| Phosphoric Acid SCHEMBL2030114 | 0.80 | FDPS (0.59) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL31030086 | 0.80 | FDPS (0.46) | FDPSSMN1; SMN2MEN1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495036-B1 | METHOD FOR THE PRODUCTION OF MONOHYDRO-PERFLUOROALKANES, BIS(PERFLUOROALKYL)PHOSPHINATES, AND PERFLUOROALKYLPHOSPHONATES | MERCK PATENT GMBH (DE) | 2009-08-19 | — | — | EP | disclosed |
| US-7145004-B2 | Method for the production of monohydro-perfluoroalkanes, bis(perfluoroalkyl)phosphinates and perfluoroalkylphosphonates | MERCK PATENT GESELLSCHAFT (DE) | 2006-12-05 | — | — | US | disclosed |
| US-20050222411-A1 | Method for the production of monohydro-perfluoroalkanes, bis (perfluoroalkyl) phosphinates and perfluoroalkylphosphonates | MERCK PATENT GMBH (DE) | 2005-10-06 | — | — | US | disclosed |
| EP-1495036-A1 | METHOD FOR THE PRODUCTION OF MONOHYDRO-PERFLUOROALKANES, BIS(PERFLUOROALKYL)PHOSPHINATES, AND PERFLUOROALKYLPHOSPHONATES | MERCK PATENT GmbH (DE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087111-A1 | METHOD FOR THE PRODUCTION OF MONOHYDRO-PERFLUOROALKANES, BIS(PERFLUOROALKYL)PHOSPHINATES, AND PERFLUOROALKYLPHOSPHONATES | MERCK PATENT GMBH (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222411-A1 | Method for the production of monohydro-perfluoroalkanes, bis (perfluoroalkyl) phosphinates and perfluoroalkylphosphonates | PFAS, PFKFB2, PHOSPHO1 | FDPS 15/4885SMN1; SMN2 4489/4885MEN1 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.