SCHEMBL3822658

SCHEMBL3822658

O=C1c2ccc(Oc3ccc4c(c3)C(=O)N(OS(=O)(=O)c3cccc(C(F)(F)F)c3)C4=O)cc2C(=O)N1OS(=O)(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.48
KDM4E B2RXH2 6/20 0.48
ALDH1A1 P00352 6/20 0.48
MAPT P10636 5/20 0.48
HPGD P15428 5/20 0.48
NR3C1 P04150 1/20 0.46
PGR P06401 1/20 0.46
AR P10275 1/20 0.46
ESR2 Q92731 1/20 0.46
MEN1 O00255 5/20 0.45
HTT P42858 1/20 0.42
VDR P11473 3/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
KIF11 P52732 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3823498 0.89 KMT2A (0.45) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3823140 0.86 KMT2A (0.51) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3827232 0.85 KDM4E (0.47) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3824621 0.82 KDM4E (0.71) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3826861 0.79 KMT2A (0.51) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3829861 0.78 KMT2A (0.68) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3831003 0.78 KDM4E (0.52) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL3827591 0.77 KMT2A (0.47) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL6743844 0.77 KDM4E (0.62) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL4826549 0.76 CA1 (0.47) KMT2AKDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP claimed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US claimed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US claimed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP claimed
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 KMT2A 1016/4885KDM4E 2501/4885ALDH1A1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.