SCHEMBL3822666

SCHEMBL3822666

FC(F)(F)c1ccnc(-c2cccs2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
NOS3 P29474 1/20 0.49
NOS2 P35228 1/20 0.49
KDM4E B2RXH2 11/20 0.46
ALDH1A1 P00352 9/20 0.46
GAA P10253 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.43
RXFP1 Q9HBX9 1/20 0.43
KMT2A Q03164 4/20 0.43
HPGD P15428 3/20 0.43
MEN1 O00255 3/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 3/20 0.43
NPC1 O15118 2/20 0.43
SDHB P21912 2/20 0.43
HTT P42858 2/20 0.43
MAPK1 P28482 2/20 0.43
LRRK2 Q5S007 1/20 0.43
S1PR4 O95977 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3829768 0.98 SMN1; SMN2 (0.49) SMN1; SMN2NOS3NOS2KDM4EALDH1A1
SCHEMBL17049366 0.79 KDM4E (0.51) SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1
SCHEMBL810884 0.78 NOS3 (0.61) NOS3NOS2ALDH1A1GAAL3MBTL1
SCHEMBL20422050 0.75 SYK (0.52) NOS3NOS2LRRK2RAB9ACDK2
SCHEMBL30739117 0.75 SMN1; SMN2 (0.47) SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1
SCHEMBL556771 0.75 SMN1; SMN2 (0.47) SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1
SCHEMBL28726692 0.74 NOS3 (0.46) NOS3NOS2ALDH1A1GAAL3MBTL1
SCHEMBL2383189 0.74 KDM4E (0.50) SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1
SCHEMBL11562431 0.74 CCR1 (0.57) SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1
SCHEMBL14202902 0.74 SMN1; SMN2 (0.55) SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191612-B1 Luminescence device and display apparatus CANON KK (JP) 2009-09-09 EP disclosed
EP-1191612-B1 Luminescence device and display apparatus CANON KK (JP) 2009-09-09 EP disclosed
EP-2062907-A2 Metal coordination compound, luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2009-05-27 EP disclosed
US-7220495-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2007-05-22 US disclosed
US-7220495-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2007-05-22 US disclosed
US-7220495-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2007-05-22 US disclosed
US-7205054-B2 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2007-04-17 US disclosed
US-6991857-B2 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2006-01-31 US disclosed
US-20050266268-A1 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2005-12-01 US disclosed
US-20050025996-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-02-03 US disclosed
US-6821646-B2 CAPABLE OF PROVIDING A HIGH-EFFICIENCY LUMINESCENT STATE AT A HIGH BRIGHTNESS (OR LUMINANCE) FOR A LONG PERIOD WHILE MINIMIZING THE DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-23 US disclosed
US-20030054198-A1 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2003-03-20 US disclosed
CN-1364847-A Metal ligand compound, luminous device and display device CANON KK (JP) 2002-08-21 CN disclosed
EP-1211257-A2 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2002-06-05 EP disclosed
US-20020063516-A1 Limuninescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191612-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed