SCHEMBL556771

SCHEMBL556771

FC(F)(F)c1ccc(-c2cccs2)nc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
RAB9A P51151 3/20 0.46
KDM4E B2RXH2 8/20 0.44
ALDH1A1 P00352 6/20 0.44
HPGD P15428 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GAA P10253 3/20 0.44
NPC1 O15118 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CASP1 P29466 1/20 0.44
MAPK10 P53779 1/20 0.44
CASP7 P55210 1/20 0.44
CASP3 P42574 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
FYN P06241 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30739117 1.00 SMN1; SMN2 (0.47) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL3826940 0.98 SMN1; SMN2 (0.46) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL14155785 0.83 KDM4E (0.44) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL23302375 0.79 KDM4E (0.46) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL29595709 0.77 NPSR1 (0.53) SMN1; SMN2RAB9AKDM4EHPGDL3MBTL1
SCHEMBL811160 0.77 NPSR1 (0.53) SMN1; SMN2RAB9AKDM4EHPGDL3MBTL1
SCHEMBL7427844 0.77 KDM4E (0.48) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL12727899 0.76 KDM4E (0.52) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL10408880 0.76 KDM4E (0.52) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD
SCHEMBL3822666 0.75 SMN1; SMN2 (0.50) SMN1; SMN2RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304094-A Synthesis method of 3-trifluoromethyl pyridine or 3-difluoro methyl pyridine compound 瑞博(杭州)医药科技有限公司 2023-12-29 CN disclosed
EP-1349435-B1 LUMINESCENT ELEMENT AND DISPLAY CANON KK (JP) 2018-06-06 EP disclosed
US-20170029535-A1 REGULATION OF A CONTROLLED RADICAL POLYMERIZATION OF ACRYLATES BY LIGHT DOW GLOBAL TECHNOLOGIES LLC 2017-02-02 US disclosed
US-20170029535-A1 REGULATION OF A CONTROLLED RADICAL POLYMERIZATION OF ACRYLATES BY LIGHT DOW GLOBAL TECHNOLOGIES LLC 2017-02-02 US disclosed
US-9081283-B2 Spatial and temporal control of brush formation on surfaces THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-07-14 US disclosed
EP-2034000-B1 Electroluminescent iridium compounds having red-orange or red emission and devices made with such compounds DU PONT (US) 2015-05-06 EP disclosed
US-9000157-B2 Metallic compound and organic electroluminescence device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-07 US disclosed
US-20120032158-A1 Charge transport compositions and electronic devices made with such compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-09 US disclosed
US-8071975-B2 Electronic devices made with electron transport and/or anti-quenching layers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-12-06 US disclosed
US-20110184170-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME SAMSUNG ELECTRONICS CO., LTD (KR) 2011-07-28 US disclosed
EP-1520452-A2 ELECTRONIC DEVICES MADE WITH ELECTRON TRANSPORT AND/OR ANTI-QUENCHING LAYERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-04-06 EP disclosed
US-20050025996-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-02-03 US disclosed
US-6821646-B2 CAPABLE OF PROVIDING A HIGH-EFFICIENCY LUMINESCENT STATE AT A HIGH BRIGHTNESS (OR LUMINANCE) FOR A LONG PERIOD WHILE MINIMIZING THE DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-23 US disclosed
EP-1442094-A2 ELECTROLUMINESCENT IRIDIUM COMPOUNDS HAVING RED-ORANGE OR RED EMISSION AND DEVICES MADE WITH SUCH COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-08-04 EP disclosed
US-20040066135-A1 Electronic devices made with electron transport and/or anti-quenching layers LG CHEM, LTD. (KR) 2004-04-08 US disclosed
WO-2004006352-A2 ELECTRONIC DEVICES MADE WITH ELECTRON TRANSPORT AND/OR ANTI-QUENCHING LAYERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-01-15 WO disclosed
US-20030096138-A1 Electroluminescent iridium compounds having red-orange or red emission and devices made with such compounds LG CHEM, LTD. (KR) 2003-05-22 US disclosed
WO-2003040256-A2 ELECTROLUMINESCENT IRIDIUM COMPOUNDS HAVING RED-ORANGE OR RED EMISSION AND DEVICES MADE WITH SUCH COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-05-15 WO disclosed
US-20020063516-A1 Limuninescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191612-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184170-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME MT-CO1, ROS1, OXA1L SMN1; SMN2 2190/4885RAB9A 782/4885KDM4E 3090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.