Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL10788993 | 0.88 | HCAR2 (0.43) | HCAR2SMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| Styrene SCHEMBL11880649 | 0.81 | HCAR2 (0.40) | HCAR2SMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| Styrene SCHEMBL19371318 | 0.81 | HCAR2 (0.47) | HCAR2SMN1; SMN2ALDH1A1LMNAMAPT | |
| Styrene SCHEMBL10587972 | 0.80 | HCAR2 (0.42) | HCAR2POLBSMN1; SMN2ALDH1A1LMNA | |
| Ethyl Fumarate SCHEMBL1064537 | 0.79 | HCAR2 (0.55) | HCAR2ALDH1A1LMNAMAPTTHRB | |
| Acrylic Acid Methyl Ester SCHEMBL10947152 | 0.78 | HCAR2 (0.50) | HCAR2SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Styrene SCHEMBL8516972 | 0.78 | HCAR2 (0.44) | HCAR2POLBSMN1; SMN2GAAALDH1A1 | |
| Styrene SCHEMBL17746691 | 0.77 | THRB (0.53) | HCAR2POLBSMN1; SMN2GAAALDH1A1 | |
| Styrene SCHEMBL28045811 | 0.77 | HCAR2 (0.56) | HCAR2ALDH1A1LMNATHRBAPP | |
| Styrene SCHEMBL379434 | 0.77 | THRB (0.55) | HCAR2POLBSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092025-A2 | COATINGS COMPRISING TERPENE | PPG Industries Ohio, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008067095-A2 | COATINGS COMPRISING TERPENE | PPG INDUSTRIES OHIO, INC. (US) | 2008-06-05 | — | — | WO | disclosed |