Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL11880649 | 0.93 | HCAR2 (0.40) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Styrene SCHEMBL10587972 | 0.91 | HCAR2 (0.42) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Styrene SCHEMBL3822791 | 0.88 | HCAR2 (0.42) | HCAR2KDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| Ethyl Fumarate SCHEMBL250119 | 0.86 | HCAR2 (0.57) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Butyl Fumarate SCHEMBL3956267 | 0.84 | HCAR2 (0.61) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Butyl Fumarate SCHEMBL3956264 | 0.84 | HCAR2 (0.61) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Styrene SCHEMBL8945531 | 0.84 | TSHR (0.59) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Styrene SCHEMBL5698364 | 0.84 | TSHR (0.59) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Styrene SCHEMBL5698366 | 0.84 | TSHR (0.59) | HCAR2TSHRHPGDKDM4EALDH1A1 | |
| Styrene SCHEMBL164779 | 0.84 | TSHR (0.48) | HCAR2TSHRHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104283-B1 | DISPERSANTS FOR COATING COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-29 | — | — | EP | disclosed |
| US-4369232-A | POLYMERS OF ISOCYANATE ACRYLATES MODIFIED BY A FATTY AMINE AND ALKYL- OR ALKANOLAMINC; PAINTS; ENAMELS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-18 | — | — | US | disclosed |