Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829704 | 0.87 | KMT2A (0.49) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3825171 | 0.86 | RAB9A (0.53) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL3822406 | 0.85 | RAB9A (0.52) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3058928 | 0.84 | PPARG (0.42) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL3824268 | 0.83 | RAB9A (0.51) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3830147 | 0.83 | SIGMAR1 (0.50) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3826982 | 0.83 | RAB9A (0.54) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3828031 | 0.83 | RAB9A (0.50) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3822411 | 0.82 | RAB9A (0.51) | RAB9ATMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3826950 | 0.82 | RAB9A (0.51) | RAB9ATMEM97SIGMAR1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |