SCHEMBL3823271

SCHEMBL3823271

CC(C)(C)P(Cc1ccc([Si](C)(C)C(C)(C)C)cc1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2011622 0.84 NR1H2 (0.35) NR1H2NR1H3
SCHEMBL1470968 0.81 ESR1 (0.33)
SCHEMBL3311075 0.77 NR1H2 (0.35) NR1H2NR1H3
SCHEMBL5139078 0.74 NR1H2 (0.46) NR1H2NR1H3
SCHEMBL3689005 0.73 IDO1 (0.42)
SCHEMBL31019832 0.71 HRH3 (0.44)
SCHEMBL2011093 0.71 TSHR (0.42)
SCHEMBL706086 0.70 TAAR1 (0.44)
SCHEMBL19256277 0.69 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL12885589 0.68 RAB9A (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105153241-B Carbonylation ligands and their use in the carbonylation of ethylenically unsaturated compounds 卢西特国际英国有限公司 2020-05-15 CN disclosed
EP-2097429-A1 NOVEL CARBONYLATION LIGANDS AND THEIR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS Lucite International UK Limited (GB) 2009-09-09 EP disclosed
WO-2008065448-A1 NOVEL CARBONYLATION LIGANDS AND THEIR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS LUCITE INTERNATIONAL UK LIMITED (GB) 2008-06-05 WO disclosed