Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205532 | 0.84 | ATM (0.45) | NOTUMLMNACA12CA9ATM | |
| SCHEMBL3821496 | 0.83 | TACR1 (0.37) | — | |
| SCHEMBL13743012 | 0.78 | NOTUM (0.47) | NOTUMLMNACA12CA9KCNN4 | |
| SCHEMBL13637918 | 0.78 | LMNA (0.45) | LMNAGAA | |
| SCHEMBL4201299 | 0.76 | ALDH1A1 (0.52) | NOTUMLMNACA12CA9ATM | |
| SCHEMBL3814197 | 0.76 | LMNA (0.47) | NOTUMLMNACA12CA9KCNN4 | |
| SCHEMBL13742929 | 0.76 | NOTUM (0.47) | NOTUMLMNACA12CA9KCNN4 | |
| SCHEMBL4203119 | 0.75 | TACR1 (0.43) | LMNA | |
| SCHEMBL8322001 | 0.73 | TACR1 (0.38) | — | |
| SCHEMBL4205207 | 0.72 | TACR1 (0.44) | LMNAATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119356-B1 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-08-19 | — | — | EP | disclosed |
| US-6241964-B1 | (F18)(2-FLUOROMETHOXY-5-(5-TRIFLUOROMETHYL-TETRAZOLE-1-YL) -BENZYL)-((2S,3S)-2-PHENYL-PIPERIDINE-3-YL)-AMINE OR SALT; HUMAN BRAIN TISSUE IMAGING USING POSITRON EMISSION TOMOGRAPHY | MERCK & CO., INC. | 2001-06-05 | — | — | US | disclosed |