Sulfuric Acid

Sulfuric Acid

SCHEMBL3823397

COc1cccc2c1Nc1ccccc1N2C.O=S(=O)(O)O

nearest known ligand 0.44

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 2/20 0.44
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 2/20 0.38
GAA P10253 4/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 2/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
MGLL Q99685 1/20 0.36
MEN1 O00255 1/20 0.36
MITF O75030 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL30513696 1.00 CHEK1 (0.44) CHEK1KDM4EALDH1A1TDP1GAA
SCHEMBL2490578 0.94 CHEK1 (0.42) CHEK1KDM4EALDH1A1TDP1GAA
SCHEMBL31398538 0.94 CHEK1 (0.42) CHEK1KDM4EALDH1A1TDP1GAA
SCHEMBL30222706 0.91 CHEK1 (0.46) CHEK1KDM4EALDH1A1GAAKMT2A
SCHEMBL851557 0.91 CHEK1 (0.46) CHEK1KDM4EALDH1A1GAAKMT2A
Sulfuric Acid Dimethyl Ester SCHEMBL28991157 0.90 CHEK1 (0.46) CHEK1KDM4EALDH1A1TDP1GAA
Sulfuric Acid SCHEMBL10339576 0.84 ALDH1A1 (0.38) KDM4EALDH1A1TDP1GAAKMT2A
Sulfuric Acid SCHEMBL31514469 0.84 ALDH1A1 (0.38) KDM4EALDH1A1TDP1GAAKMT2A
Sulfuric Acid SCHEMBL17416113 0.82 SMN1; SMN2 (0.39) CHEK1KDM4EALDH1A1GAAKMT2A
SCHEMBL28429972 0.82 CHEK1 (0.43) CHEK1KDM4EALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7267986-B2 Method of detecting inorganic phosphoric acid, pyrophosphate and nucleic acid, and method of typing SNP sequence of DNA MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2007-09-11 US claimed
US-20040197803-A1 Method, primer and kit for determining base type MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-10-07 US claimed
US-20040171100-A1 Method of detecting inorganic phosphoric acid, pyrophosphate and nucleic acid, and method of typing SNP sequence of DNA MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-09-02 US claimed
EP-1378575-A1 METHOD OF DETECTING INORGANIC PHOSPHORIC ACID, PYROPHOSPHORIC ACID AND NUCLEIC ACID AND METHOD OF TYPING SNP SEQUENCE OF DNA MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-01-07 EP claimed
EP-0794429-B1 Cholesterol sensor MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-07-31 EP claimed
US-6214612-B1 Cholesterol sensor containing electrodes, cholesterol dehydrogenase, nicotinamide adenine dinucleotide and oxidized electron mediator MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-04-10 US claimed
EP-0794429-A1 Cholesterol sensor MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-09-10 EP claimed
CN-107884462-B Biosensor, method for producing same, method for measuring concentration of glucose or lactic acid, and concentration measuring system 爱科来株式会社 2021-10-01 CN disclosed
US-7604776-B2 Sample-liquid analysis disc and method for analyzing sample mixture liquid PANASONIC CORPORATION (JP) 2009-10-20 US disclosed
US-20080227217-A1 SAMPLE-LIQUID ANALYSIS DISC AND METHOD FOR ANALYZING SAMPLE MIXTURE LIQUID MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-09-18 US disclosed
CN-100342029-C Process for preparation of enzyme electrode COUNCIL SCIENT IND RES (IN) 2007-10-10 CN disclosed
US-7267986-B2 Method of detecting inorganic phosphoric acid, pyrophosphate and nucleic acid, and method of typing SNP sequence of DNA MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2007-09-11 US disclosed
US-7267837-B2 Enzyme electrode and process for preparation thereof KUMAR ARUN 2007-09-11 US disclosed
US-20040171100-A1 Method of detecting inorganic phosphoric acid, pyrophosphate and nucleic acid, and method of typing SNP sequence of DNA MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-09-02 US disclosed
US-20040149577-A1 Enzyme electrode and process for preparation thereof KUMAR ARUN (IN) 2004-08-05 US disclosed
EP-1378575-A1 METHOD OF DETECTING INORGANIC PHOSPHORIC ACID, PYROPHOSPHORIC ACID AND NUCLEIC ACID AND METHOD OF TYPING SNP SEQUENCE OF DNA MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-01-07 EP disclosed
EP-0794429-B1 Cholesterol sensor MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-07-31 EP disclosed
US-6214612-B1 Cholesterol sensor containing electrodes, cholesterol dehydrogenase, nicotinamide adenine dinucleotide and oxidized electron mediator MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-04-10 US disclosed
US-6214612-B1 Cholesterol sensor containing electrodes, cholesterol dehydrogenase, nicotinamide adenine dinucleotide and oxidized electron mediator MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-04-10 US disclosed
EP-0794429-A1 Cholesterol sensor MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-09-10 EP disclosed