SCHEMBL3823482

SCHEMBL3823482

CCCCCCn1c2ccc(Br)cc2c2cc(Br)ccc21

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.54
PSEN1 P49768 4/20 0.52
PSEN2 P49810 4/20 0.52
APH1B Q8WW43 4/20 0.52
NCSTN Q92542 4/20 0.52
APH1A Q96BI3 4/20 0.52
PSENEN Q9NZ42 4/20 0.52
CNR2 P34972 10/20 0.48
MAPT P10636 2/20 0.46
RORA P35398 1/20 0.45
RORC P51449 1/20 0.45
RORB Q92753 1/20 0.45
DNM1 Q05193 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28299672 1.00 SIGMAR1 (0.54) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL3339737 1.00 SIGMAR1 (0.54) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL751367 1.00 SIGMAR1 (0.54) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL29779351 1.00 SIGMAR1 (0.54) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL29393803 1.00 SIGMAR1 (0.54) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL11127173 1.00 SIGMAR1 (0.54) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL11909992 0.98 SIGMAR1 (0.55) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL926107 0.97 PSEN1 (0.53) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL28014993 0.97 PSEN1 (0.53) SIGMAR1PSEN1PSEN2APH1BNCSTN
SCHEMBL28585812 0.94 PSEN1 (0.58) SIGMAR1PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133385-B Hole transport material with carbazole as core and thiophene or phenoxazine as end group, and synthesis method and application thereof 华南师范大学 2023-05-23 CN claimed
CN-115975094-A Carbon nitrogen oxygen arylamine high molecular fluorescent polymer and preparation method and application thereof 广东工业大学 2023-04-18 CN claimed
CN-114133385-A Hole transport material with carbazole as core and phenothiazine or phenoxazine as end group, and synthesis method and application thereof 华南师范大学 2022-03-04 CN claimed
CN-113121409-A Organic fluorescent material with information deep hiding function, preparation and application 太原理工大学 2021-07-16 CN claimed
US-7906724-B2 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-03-15 US claimed
US-20090032106-A1 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2009-02-05 US claimed
US-11874578-B2 High transparency electrochromic polymers AMBILIGHT INC. (KY) 2024-01-16 US disclosed
US-11874578-B2 High transparency electrochromic polymers AMBILIGHT INC. (KY) 2024-01-16 US disclosed
US-20230251541-A1 HIGH TRANSPARENCY ELECTROCHROMIC POLYMERS AMBILIGHT INC. (KY) 2023-08-10 US disclosed
CN-114133385-B Hole transport material with carbazole as core and thiophene or phenoxazine as end group, and synthesis method and application thereof 华南师范大学 2023-05-23 CN disclosed
CN-115975094-A Carbon nitrogen oxygen arylamine high molecular fluorescent polymer and preparation method and application thereof 广东工业大学 2023-04-18 CN disclosed
CN-114133385-A Hole transport material with carbazole as core and phenothiazine or phenoxazine as end group, and synthesis method and application thereof 华南师范大学 2022-03-04 CN disclosed
CN-113121409-A Organic fluorescent material with information deep hiding function, preparation and application 太原理工大学 2021-07-16 CN disclosed
US-7906724-B2 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-03-15 US disclosed
CN-101555357-A Dye compounds TAIWAN EVERLIGHT CHEMICAL IND (CN) 2009-10-14 CN disclosed
US-7569704-B1 Dye compound EVERLIGHT USA, INC. (US) 2009-08-04 US disclosed
US-7569704-B1 Dye compound EVERLIGHT USA, INC. (US) 2009-08-04 US disclosed
US-20090032106-A1 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2009-02-05 US disclosed
CN-1687066-A Conjugated polymer material with lateral group possessing function of guanine, preparing process and application UNIV FUDAN (CN) 2005-10-26 CN disclosed
US-6344286-B1 CONTAINING FLUORENE, CARBAZOLE AND/OR BENZENE GROUPS HANWHA CHEMICAL CORPORATION (KR) 2002-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090032106-A1 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics NECTIN4, VCL, VDAC3 SIGMAR1 4356/4885PSEN1 3894/4885PSEN2 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.