Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | RORB | Q92753 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299672 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL751367 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3823482 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29779351 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29393803 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11127173 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11909992 | 0.98 | SIGMAR1 (0.55) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL926107 | 0.97 | PSEN1 (0.53) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28014993 | 0.97 | PSEN1 (0.53) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28585812 | 0.94 | PSEN1 (0.58) | SIGMAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727690-B2 | Iridium complex, carbazole derivatives and copolymer having the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-06-01 | — | — | US | disclosed |
| EP-1923385-B1 | Iridium complex, carbazole derivatives and copolymer having the same | KWANGJU INST SCI & TECH (KR) | 2009-05-27 | — | — | EP | disclosed |
| US-20080177084-A1 | IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-07-24 | — | — | US | disclosed |
| EP-1923385-A1 | Iridium complex, carbazole derivatives and copolymer having the same | Gwangju Institute of Science and Technology (KR) | 2008-05-21 | — | — | EP | disclosed |
| US-20080054794-A1 | Organic Electroluminescence Device, Image Display Apparatus and Lighting Apparatus Including the Same, Charge Transport Material and Charge Transport Layer Forming Ink Including the Same | Fujiki, Michiya (JP) | 2008-03-06 | — | — | US | disclosed |
| WO-2006001469-A2 | ORGANIC ELECTROLUMINESCENCE DEVICE, IMAGE DISPLAY APPARATUS AND LIGHTING APPARATUS INCLUDING THE SAME CHARGE TRANSPORT MATERIAL | SHARP KABUSHIKI KAISHA (JP) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177084-A1 | IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME | INTS9, HIRIP3, HELZ | SIGMAR1 3086/4885PSEN1 4666/4885PSEN2 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.