Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828270 | 0.93 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL3825328 | 0.84 | MEN1 (0.47) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL1361571 | 0.84 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL3825321 | 0.84 | MEN1 (0.47) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL15041982 | 0.82 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL15041993 | 0.82 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL14477979 | 0.82 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL15042138 | 0.82 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL12668088 | 0.82 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL15042013 | 0.82 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |