Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825325 | 0.90 | DGKA (0.45) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL3823823 | 0.84 | MEN1 (0.40) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL3823832 | 0.84 | MEN1 (0.40) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL14990529 | 0.83 | BRD4 (0.44) | CYP3A4ATMTDP1DGKATRPV1 | |
| SCHEMBL14990528 | 0.83 | BRD4 (0.44) | CYP3A4ATMTDP1DGKATRPV1 | |
| SCHEMBL1360711 | 0.80 | PPARG (0.47) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL3823547 | 0.76 | BRD4 (0.51) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL333602 | 0.76 | TDP1 (0.77) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL9838603 | 0.76 | TDP1 (0.77) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL10657519 | 0.76 | TDP1 (0.77) | TSHRCYP3A4ATMTDP1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |