Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823823 | 1.00 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3825321 | 0.89 | MEN1 (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3825328 | 0.89 | MEN1 (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14477970 | 0.89 | L3MBTL1 (0.48) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3844849 | 0.89 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL16511627 | 0.84 | PRSS1 (0.43) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3823829 | 0.84 | TSHR (0.44) | ALDH1A1TSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL12667785 | 0.84 | CYP3A4 (0.46) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1361571 | 0.83 | L3MBTL1 (0.42) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14990686 | 0.82 | CYP3A4 (0.45) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |