SCHEMBL3823904

SCHEMBL3823904

NNC(=O)C(CO)(CO)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
HIF1A Q16665 1/20 0.47
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP3A4 P08684 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MMP8 P22894 5/20 0.41
CYP1A2 P05177 3/20 0.40
TSHR P16473 2/20 0.40
RECQL P46063 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPK1 P28482 1/20 0.39
SLC6A2 P23975 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
MAPT P10636 1/20 0.38
PLA2G10 O15496 1/20 0.38
PLA2G2A P14555 1/20 0.38
FDPS P14324 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916090 0.79 SMN1; SMN2 (0.55) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL9721523 0.78 SMN1; SMN2 (0.55) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL11993052 0.75 SLC6A2 (0.52) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL8504875 0.74 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL3077561 0.72 HIF1A (0.57) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL6468187 0.72 LMNA (0.50) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL27782350 0.72 SMN1; SMN2 (0.57) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL3361668 0.72 FDPS (0.60) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP1A2
SCHEMBL2710968 0.71 CYP3A4 (0.47) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4
SCHEMBL2710822 0.71 CYP3A4 (0.47) SMN1; SMN2HIF1ACYP2C9CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423486-B1 None US disclosed
EP-0990946-B1 Heat-developable photosensitive material FUJIFILM CORP (JP) 2009-09-09 EP disclosed
EP-1020760-B1 Heat developable image recording material FUJIFILM CORP (JP) 2007-11-14 EP disclosed
EP-1026545-B1 Heat developable photosensitive material FUJIFILM CORP (JP) 2007-09-26 EP disclosed
EP-0974866-B1 Heat-developable image-recording material FUJI PHOTO FILM CO LTD (JP) 2006-10-18 EP disclosed
EP-1134611-B1 Photothermographic material and method for forming images FUJI PHOTO FILM CO LTD (JP) 2005-07-20 EP disclosed
EP-1045284-B1 Heat developing method for heat developable image recording material FUJI PHOTO FILM CO LTD (JP) 2005-07-06 EP disclosed
EP-0911691-B2 Recording elements and making methods FUJI PHOTO FILM CO LTD (JP) 2005-04-13 EP disclosed
EP-0838722-B1 Photothermographic material containing a 2,3-dihydrothiazole derivative FUJI PHOTO FILM CO LTD (JP) 2005-01-12 EP disclosed
US-6824962-B2 SILVER HALIDE MATERIAL CONTAINS A COMPOUND PRODUCING IMAGEWISE A CHEMICAL SPECIES THAT CAN FORM DEVELOPMENT INITIATION POINTS ON AND IN THE VICINITY OF THE NON-PHOTOSENSITIVE ORGANIC SILVER SALT AND AN ORGANIC GOLD COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-0911690-A1 Photothermographic elements adapted for laser exposure FUJI PHOTO FILM CO., LTD. (JP) 1999-04-28 EP disclosed
EP-0911692-A2 Photothermographic elements FUJI PHOTO FILM CO., LTD. (JP) 1999-04-28 EP disclosed
EP-0903629-A1 HEAT DEVELOPING PHOTOSENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
EP-0902322-A1 Thermographic image-recording elements FUJI PHOTO FILM CO., LTD. (JP) 1999-03-17 EP disclosed
US-5869229-A HIGH SENSITIVITY IN INFRARED REGION AND A MINIMAL SENSITIVITY CHANGE WITH VARYING STORAGE CONDITIONS FUJI PHOTO FILM CO., LTD. (JP) 1999-02-09 US disclosed
EP-0887701-A1 Method for preparing photosensitive image forming medium coating solution, and photothermographic elements FUJI PHOTO FILM CO., LTD. (JP) 1998-12-30 EP disclosed
EP-0883022-A1 Coating method for thermographic imaging element, coating solution for thermographic image forming layer, thermographic imaging element, and photothermographic imaging element FUJI PHOTO FILM CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0838722-A2 Photothermographic material, novel 2,3-dihydrothiazole derivative, and photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0829753-A1 Photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-18 EP disclosed
EP-0599463-A2 High speed, dry processed printing plate construction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-01 EP disclosed