SCHEMBL3823917

SCHEMBL3823917

Nc1ccc(N=Nc2ccc3c(O)cc(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 3/20 0.71
NSD2 O96028 1/20 0.71
DUSP3 P51452 1/20 0.71
PTPN5 P54829 1/20 0.71
PTPN11 Q06124 1/20 0.71
NT5E P21589 3/20 0.58
CTDSP1 Q9GZU7 1/20 0.58
PRMT1 Q99873 1/20 0.51
CYP2C9 P11712 3/20 0.50
CYP1A2 P05177 1/20 0.50
ENPP2 Q13822 3/20 0.48
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CYP2C19 P33261 2/20 0.45
HSD17B10 Q99714 2/20 0.45
SUMO2 P61956 1/20 0.44
SUMO1 P63165 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP2 Q9HC62 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1485998 0.89 CASP6 (0.57) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL2678435 0.84 CASP6 (0.64) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL2678429 0.84 CASP6 (0.64) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL8754086 0.84 CA12 (0.54) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL154124 0.84 CASP6 (1.00) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL11413465 0.84 CASP6 (1.00) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL29399528 0.84 CASP6 (1.00) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL3831401 0.83 PRMT1 (0.58) CASP6NSD2DUSP3PTPN5PTPN11
Water SCHEMBL4869253 0.82 CASP6 (0.97) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL4115392 0.82 CASP6 (0.97) CASP6NSD2DUSP3PTPN5PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1614719-B1 AZO COMPOUND AND SALT THEREOF NIPPON KAYAKU KK (JP) 2009-09-09 EP disclosed
US-7304147-B2 Azo compound and salt thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-12-04 US disclosed
US-20070079740-A1 Azo compound and salt thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-04-12 US disclosed
US-7108897-B2 Dye type polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-09-19 US disclosed
EP-1614719-A1 AZO COMPOUND AND SALT THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2006-01-11 EP disclosed
US-20050003109-A1 Dye type polarizing plate OISO SHOJI (JP) 2005-01-06 US disclosed
US-6790490-B1 POLYVINYL ALCOHOL FILM CONTAINING WATER SOLUBLE TRIS- OR POLYAZO DYES; DURABILITY; GREEN CHANNEL OF LIQUID CRYSTAL PROJECTORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2004-09-14 US disclosed
EP-1203969-A1 POLARIZER COMPRISING DYE Nippon Kayaku Kabushiki Kaisha (JP) 2002-05-08 EP disclosed