Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.64 |
| ▸ | NSD2 | O96028 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | CD40 | P25942 | 1/20 | 0.52 |
| ▸ | CD40LG | P29965 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678429 | 1.00 | CASP6 (0.64) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL27100624 | 0.87 | ENPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL10587918 | 0.87 | ENPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL13474894 | 0.87 | ENPP2 (0.60) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL29702431 | 0.87 | ENPP2 (0.59) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL20735380 | 0.86 | CD40 (0.61) | ENPP2CD40CD40LGCYP1A2PRMT1 | |
| SCHEMBL29702399 | 0.86 | ENPP2 (0.58) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL3823917 | 0.84 | CASP6 (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL10625256 | 0.83 | ENPP2 (0.67) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL8972293 | 0.83 | PHLPP2 (0.53) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8175860-B2 | Method of inhibiting the growth of Helicobacter pylori | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-08 | — | — | US | disclosed |
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | HPD, HAAO, HK1 | CASP6 4091/4885NSD2 4029/4885DUSP3 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.