SCHEMBL3824441

SCHEMBL3824441

FC(F)(F)c1ccc(-c2cc3ccccc3s2)nc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.53
CYP11B1 P15538 2/20 0.49
CYP11B2 P19099 2/20 0.49
CYP19A1 P11511 1/20 0.45
DCK P27707 1/20 0.40
APP P05067 2/20 0.40
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
PIK3CG P48736 1/20 0.39
KCNH2 Q12809 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
TRPV3 Q8NET8 1/20 0.37
IKBKB O14920 2/20 0.37
CHUK O15111 1/20 0.37
IKBKG Q9Y6K9 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CASP3 P42574 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3826013 0.99 KDM1A (0.52) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL28911362 0.80 KDM1A (0.57) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL4821816 0.77 KDM1A (0.57) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL13017787 0.77 KDM1A (0.57) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL13201335 0.77 KDM1A (0.64) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL4014804 0.77 KDM1A (0.57) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL4659871 0.76 KDM1A (0.56) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL19992542 0.75 KDM1A (0.46) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL12376481 0.74 KDM1A (0.54) KDM1ACYP11B1CYP11B2CYP19A1DCK
SCHEMBL19794423 0.73 KDM1A (0.53) KDM1ACYP11B1CYP11B2CYP19A1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191612-B1 Luminescence device and display apparatus CANON KK (JP) 2009-09-09 EP disclosed
EP-1191612-B1 Luminescence device and display apparatus CANON KK (JP) 2009-09-09 EP disclosed
US-7220495-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2007-05-22 US disclosed
US-7220495-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2007-05-22 US disclosed
US-7220495-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2007-05-22 US disclosed
US-20060093852-A1 Phosphorescent and luminescent conjugated polymers and their use in electroluminescent assemblies H.C. STARCK GMBH (DE) 2006-05-04 US disclosed
US-20050025996-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-02-03 US disclosed
US-6821646-B2 CAPABLE OF PROVIDING A HIGH-EFFICIENCY LUMINESCENT STATE AT A HIGH BRIGHTNESS (OR LUMINANCE) FOR A LONG PERIOD WHILE MINIMIZING THE DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-23 US disclosed
US-20020063516-A1 Limuninescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191612-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed