Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | DCK | P27707 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 4/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009999 | 0.92 | KDM1A (0.50) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL13017787 | 0.81 | KDM1A (0.57) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL4821816 | 0.81 | KDM1A (0.57) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL28911362 | 0.81 | KDM1A (0.57) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL13201335 | 0.81 | KDM1A (0.64) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL4659871 | 0.79 | KDM1A (0.56) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL12376481 | 0.78 | KDM1A (0.54) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL19794423 | 0.77 | KDM1A (0.53) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL3824441 | 0.77 | KDM1A (0.53) | KDM1ACYP11B1CYP11B2CYP19A1APP | |
| SCHEMBL403651 | 0.76 | CYP19A1 (0.60) | KDM1ACYP11B1CYP11B2CYP19A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
| EP-1501907-B1 | SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS | CAMBRIDGE ENTPR LTD (GB) | 2016-07-27 | — | — | EP | disclosed |
| US-9023978-B2 | Solution-processable phosphorescent materials | CAMBRIDGE ENTERPRISE LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| US-9023978-B2 | Solution-processable phosphorescent materials | CAMBRIDGE ENTERPRISE LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| US-8697872-B2 | Boron compounds and uses thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-04-15 | — | — | US | disclosed |
| US-20120253044-A1 | Boron Compounds and Uses Thereof | WANG, SUNING (CA) | 2012-10-04 | — | — | US | disclosed |
| EP-2264123-A2 | Solution-processable phosphorescent materials | Cambridge Display Technology Limited (GB) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009082043-A1 | IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE | DONGWOO FINE-CHEM CO., LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | KDM1A 4569/4885CYP11B1 3601/4885CYP11B2 3300/4885 |
| US-20120253044-A1 | Boron Compounds and Uses Thereof | BRI3BP, BRSK1, BROX | KDM1A 1675/4885CYP11B1 1608/4885CYP11B2 1492/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | KDM1A 4106/4885CYP11B1 2170/4885CYP11B2 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.